6-chloro-1,3-dimethyl-5-(4-nitrobenzyl)-1,3-dihydropyrazolo[3,4,5-de]phthalazine | 1132953-61-7

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并吡唑类
• 英文名称: 6-chloro-1,3-dimethyl-5-(4-nitrobenzyl)-1,3-dihydropyrazolo[3,4,5-de]phthalazine
• CAS: 1132953-61-7
• 化学式: C₁₇H₁₄ClN₅O₂
• 分子量: 355.783
• InChiKey: LSRMTFYICDZALM-UHFFFAOYSA-N

反应信息

• 作为产物：
  描述：

  4,7-dichloro-3-(4-nitrobenzylidene)-3H-isobenzofuran-1-one 、 甲基肼 以34%的产率得到6-chloro-1,3-dimethyl-5-(4-nitrobenzyl)-1,3-dihydropyrazolo[3,4,5-de]phthalazine
  参考文献：
  名称：

  Pyrazolo[3,4,5-de]phthalazine. Syntheses of a practically unknown heterocyclic system

  摘要：

  Simple procedures for the synthesis of 1,3-dihydropyrazolo[3,4,5-de]phthalazines (2), a practically novel type of heterocyclic compounds, have been developed. Compounds equally substituted at positions N-1 and N-3 can be directly obtained from 4,7-dihalogenated benzalphthalides (1). Those with different R-2 and R-3 substituents are prepared through intermediate phthalazin-1-ones (3), whose synthesis is also considered. (C) 2008 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2008.12.072