5-(alpha-Methylvanillylidene)rhodanine | 200711-74-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 酚类
• 英文名称: 5-(alpha-Methylvanillylidene)rhodanine
• 英文别名: (5E)-5-[1-(4-hydroxy-3-methoxyphenyl)ethylidene]-2-sulfanylidene-1,3-thiazolidin-4-one
• CAS: 200711-74-6
• 化学式: C₁₂H₁₁NO₃S₂
• 分子量: 281.4
• InChiKey: GJNAWIXSTWSMGS-UXBLZVDNSA-N

物化性质

• 密度：
  1.48±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3
• 重原子数：
  18
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.17
• 拓扑面积：
  116
• 氢给体数：
  2
• 氢受体数：
  5

文献信息

• COMPOSITIONS AND METHODS FOR CONTROLLING NEURONAL EXCITATION
  申请人：Peterson Randall

  公开号：US20140330195A1

  公开（公告）日：2014-11-06

  Embodiments of the technology described herein relate, at least in part, to methods of modulating the activity of a neuron by contacting the neuron with a photo-sensitive TrpA1 agonist and then illuminating the neuron with electromagnetic radiation. Also described herein are photo-sensitive TrpA1 agonists.
• US9486447B2
  申请人：——

  公开号：US9486447B2

  公开（公告）日：2016-11-08
• [EN] COMPOSITIONS AND METHODS FOR CONTROLLING NEURONAL EXCITATION<br/>[FR] COMPOSITIONS ET PROCÉDÉS DESTINÉS À RÉGULER L'EXCITATION NEURONALE
  申请人：GEN HOSPITAL CORP

  公开号：WO2012174049A2

  公开（公告）日：2012-12-20

  Embodiments of the technology described herein relate, at least in part, to methods of modulating the activity of a neuron by contacting the neuron with a photo-sensitive TrpA1 agonist and then illuminating the neuron with electromagnetic radiation. Also described herein are photo-sensitive TrpA1 agonists.