N-(2-isopropyl-1(3)H-imidazol-4-yl)-isobutyramide | 62948-78-1

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: N-(2-isopropyl-1(3)H-imidazol-4-yl)-isobutyramide
• 英文别名: 2-isopropyl-4-(2-methyl-1-oxo-propyl)amino-imidazole；2-methyl-N-(2-propan-2-yl-1H-imidazol-5-yl)propanamide
• CAS: 62948-78-1
• 化学式: C₁₀H₁₇N₃O
• 分子量: 195.264
• InChiKey: WBMAIGDITIIPQK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.8
• 重原子数：
  14
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.6
• 拓扑面积：
  57.8
• 氢给体数：
  2
• 氢受体数：
  2

文献信息

• CTB-PI POLYAMIDE CONJUGATE FOR ACTIVATING EXPRESSION OF SPECIFIC GENE
  申请人：KYOTO UNIVERSITY

  公开号：US20190255182A1

  公开（公告）日：2019-08-22

  The present invention provides: a histone modification control agent for activating expression of a specific gene, i.e., a complex including a histone acetylation enzyme activator useful as an agent for activating a specific gene, and a polyamide for recognizing a regulatory region of a target gene; and a method for manufacturing the same. This complex specifically activates a group of genes relating to maintenance and/or differentiation of stem cells or precursor cells.