6-Cyclohexyl-11-hydroxy-8-(2-hydroxyacetyl)-9,13-dimethyl-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icosa-14,17-dien-16-one

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 类固醇和类固醇衍生物
• 英文名称: 6-Cyclohexyl-11-hydroxy-8-(2-hydroxyacetyl)-9,13-dimethyl-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icosa-14,17-dien-16-one
• 化学式: C₂₈H₃₈O₆
• 分子量: 470.6
• InChiKey: OXPLANUPKBHPMS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.7
• 重原子数：
  34
• 可旋转键数：
  3
• 环数：
  6.0
• sp3杂化的碳原子比例：
  0.79
• 拓扑面积：
  93.1
• 氢给体数：
  2
• 氢受体数：
  6

文献信息

• PHARMACEUTICAL FORMULATION COMPRISING CICLESONIDE
  申请人：Boehringer Ingelheim Vetmedica GmbH

  公开号：EP3473255A1

  公开（公告）日：2019-04-24

  The invention relates to the field of medicine, in particular to the field of veterinary medicine. The invention relates to a pharmaceutical (medicament) formulation of glucocorticoids, especially ciclesonide or a pharmaceutically acceptable derivative thereof.

  本发明涉及医学领域，特别是兽医学领域。本发明涉及一种糖皮质激素，特别是环索奈德或其药学上可接受的衍生物的药物（药品）制剂。
• AEROSOL FORMULATION FOR THE INHALATION OF BETA AGONISTS
  申请人：RADAU Kirsten

  公开号：US20080041370A1

  公开（公告）日：2008-02-21

  The present invention relates to a propellant-free aerosol formulation which contains one or more compounds of general formula 1, wherein the groups R 1 , R 2 , R 3 and X − may have the meanings indicated in the claims and in the specification, and one other active substance 2, for inhalation.
• [EN] PHARMACEUTICAL FORMULATION COMPRISING CICLESONIDE<br/>[FR] FORMULATION PHARMACEUTIQUE COMPRENANT DU CICLÉSONIDE
  申请人：BOEHRINGER INGELHEIM VETMED

  公开号：WO2014096116A1

  公开（公告）日：2014-06-26

  The invention relates to the field of medicine, in particular to the field of veterinary medicine. The invention relates to a pharmaceutical (medicament) formulation of glucocorticoids, especially ciclesonide or a pharmaceutically acceptable derivative thereof.