1,3-Hexanediol, 2-(methylamino)- | 1822540-33-9

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: 1,3-Hexanediol, 2-(methylamino)-
• 英文别名: 2-(methylamino)hexane-1,3-diol
• CAS: 1822540-33-9
• 化学式: C₇H₁₇NO₂
• 分子量: 147.22
• InChiKey: IYRZEUCKJCKYGK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.2
• 重原子数：
  10
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  52.5
• 氢给体数：
  3
• 氢受体数：
  3

文献信息

• OIL-IN-WATER EMULSIFIED COSMETIC COMPOSITION
  申请人：YAMAMOTO Yumiko

  公开号：US20100311836A1

  公开（公告）日：2010-12-09

  The present invention relates to an oil-in-water emulsified cosmetic composition, which contains an emulsion having (A) a sphingosine represented by formula (1), (B) an acid compound selected from inorganic acids and organic acids having 5 or less carbon atoms, and (C) a ceramide represented by formula (2); and another emulsion having (D) an oil component selected from polar oils and hydrocarbon oils, and (E) a surfactant. (wherein, R 1 represents a hydrocarbon group which may have a substituent; Y represents methylene, methine or O; X 1 , X 2 and X 3 each represent H, OH or acetoxy group; X 4 represents H, acetyl group or the like; R 2 and R 3 each represents H, OH or the like; R represents H, amidino group or the like; and a stands for 2 or 3) (wherein, R 7 represents a hydrocarbon group which may have a substituent, or H; Z represents methylene, methine or O; X 5 , X 6 and X 7 each represent H, OH or acetoxy group; X 4 represents H, acetyl group or the like; R 8 and R 9 each represent H, OH or the like; R 10 represents a hydrocarbon group which may have a substituent; and R 11 represents H or a hydrocarbon group which may have a substituent). The oil-in-water emulsified cosmetic composition contains a ceramide and is excellent in emulsion stability.
• Reverse Vesicle
  申请人：Okubo Koji

  公开号：US20110263714A1

  公开（公告）日：2011-10-27

  The reverse vesicle composition of the present invention includes (A) a sphingosine represented by formula (1) (wherein R 1 represents a C4 to C30 linear alkyl group which may be substituted by a hydroxyl group, a carbonyl group, or an amino group; Y represents a methylene group, a methine group, or an oxygen atom; each of X 1 , X 2 , and X 3 represents a hydrogen atom, a hydroxyl group, or an acetoxy group; X 4 represents a hydrogen atom, an acetyl group, or a glyceryl group, or forms an oxo group together with the adjacent oxygen atom (wherein when Y is a methine group, one of X 1 and X 2 is a hydrogen atom, and the other is absent, and when X 4 forms an oxo group, X 3 is absent); each of R 2 and R 3 represents a hydrogen atom, a hydroxyl group, a hydroxymethyl group, or an acetoxymethyl group; a is a number of 2 or 3; each of (R) a represents a hydrogen atom, an amidino group, or a linear-chain alkyl group optionally having a substituent selected from among a hydroxyl group, a hydroxyalkoxy group, an alkoxy group, and an acetoxy group and containing 1 to 8 carbon atoms in total; and the broken line represents an optional unsaturated bond), (B) a C16 to C30 fatty acid, (C) a hydrocarbon oil, (D) an ester oil which is in liquid form at 25° C., and (F) water, wherein the ratio by mass of ingredient (C) to ingredient (D) satisfies the following relationship: 1≦(C)/(D)<1000, and the composition contains a surfactant having a molecular weight of 1,000 or less in an amount of 1 mass % or less.
• EMULSIFIED COMPOSITION
  申请人：Orita Masanori

  公开号：US20120108661A1

  公开（公告）日：2012-05-03

  The emulsion composition of the present invention contains (A) 0.001 to 10 wt. % of an organic compound having two or more hydroxyl groups, an inorganic value of 220 to 450, and an organic value of 300 to 1,000; (B) 0.001 to 10 wt. % of an organic compound having one hydroxyl group, an inorganic value of 100 to 200, and an organic value of 280 to 700; (C) 0.001 to 10 wt. % of a compound represented by formula (2): wherein R 1 is a C4 to C30 hydrocarbon group; Z is a methylene group, a methine group, or an oxygen atom; X 1 , X 2 , X 3 is a hydrogen atom, a hydroxyl group, or an acetoxy group; X 4 is a hydrogen atom, an acetyl group, or a glyceryl group; each of R 2 and R 3 a hydrogen atom, a hydroxyl group, a hydroxymethyl group, or an acetoxymethyl group; R 4 is a C5 to C60 hydrocarbon group; and R 5 is a hydrogen atom or a hydrocarbon group containing 1 to 30 carbon atoms in total; (D) 0.00012 to 10 wt. % of at least one compound selected from the group consisting of a nonionic surfactant having a polyoxyethylene group and an HLB of 10 or higher, an ionic surfactant, and a sphingosine salt; (E) 0.003 to 15 wt. % of at least one compound selected from the group consisting of a sugar alcohol selected from the group consisting of erythritol, threitol, xylitol, and mannitol, a disaccharide, and a trisaccharide; and (F) water.
• OIL-BASED COMPOSITION
  申请人：Okubo Koji

  公开号：US20120295989A1

  公开（公告）日：2012-11-22

  A method for producing a gel-like oily composition including the following components (A), (B), and (C): (A) 4 to 60% by weight of a sphingosine represented by the formula (1) (wherein R 1 represents a hydrocarbon group having 4 to 30 carbon atoms; Y represents a methylene group, a methine group, or an oxygen atom; X 1 , X 2 , and X 3 each represent a hydrogen atom, a hydroxyl group, or an acetoxy group; X 4 represents a hydrogen atom, an acetyl group, or a glyceryl group or forms an oxo group together with the adjacent oxygen atom; R 2 and R 3 each represent a hydrogen atom, a hydroxyl group, a hydroxymethyl group, or an acetoxymethyl group; “R”s each represent a hydrogen atom or an amidino group or represent a hydrocarbon group having a total of 1 to 8 carbon atoms; “a” represents a number of 2 or 3; and a bond represented by a broken line and a solid line indicates a saturated bond or an unsaturated bond); (B) 0.5 to 10% by weight of an anionic polymer having a carboxyl group; and (C) 30 to 95.5% by weight of an oil in a liquid state at 25° C. selected from a hydrocarbon oil, an ester oil, and an ether oil, the method including mixing the components (A), (B), and (C) and heating the resultant mixture to a temperature equal to or more than a melting point of the component (A) to neutralize the component (B) with the component (A) to form a salt.
• VESICLE COMPOSITION
  申请人：Yamamoto Yumiko

  公开号：US20140018443A1

  公开（公告）日：2014-01-16

  The present invention is to provide a vesicle composition comprising the following components (A), (B) and (C): (A) 0.0001 to 20 mass % of an organic acid represented by general formula (1): wherein R 1 represents a natural sterin having a single hydroxy group or a hydrogenated product thereof or a residue which remains after a hydrogen atom is removed from the hydroxy group of bile acid, R 2 represents a divalent hydrocarbon group having 1 to 24 carbon atoms, M represents a hydrogen atom, an alkali metal, an alkali earth metal, ammonium, an alkanolammonium having 2 to 9 carbon atoms in total, an alkylammonium or alkenylammonium having 1 to 22 carbon atoms in total, pyridinium substituted with an alkyl group or alkenyl group having 1 to 18 carbon atoms or a basic amino acid, (B) 0.0001 to 10 mass % of a sphingosine, and (C) water, and having a pH of 2 to 11.