(E)-diethyl 1-(2-methyl-5-ethoxycarbonylfur-3-yl)-2-hydroxyethylenephosphonate | 1421862-22-7

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 呋喃
• 英文名称: (E)-diethyl 1-(2-methyl-5-ethoxycarbonylfur-3-yl)-2-hydroxyethylenephosphonate
• CAS: 1421862-22-7
• 化学式: C₁₄H₂₁O₇P
• 分子量: 332.29
• InChiKey: UOICWZQMFRWJGN-UKTHLTGXSA-N

反应信息

• 作为产物：
  描述：

  ethyl 2-methyl-3-<(diethoxyphosphinyl)methyl>furan-5-carboxylate 、 甲酸乙酯 在 sodium 作用下， 以 甲苯 为溶剂， 以36%的产率得到(E)-diethyl 1-(2-methyl-5-ethoxycarbonylfur-3-yl)-2-hydroxyethylenephosphonate
  参考文献：
  名称：

  Enol phosphates of phosphorylated derivatives of furylacetic aldehyde and furylpiruvic acid

  摘要：

  Phosphorylated derivatives of isomeric furylacetic aldehydes and furylpiruvic acids have been synthesized via formylation and oxalylation of dialkyl (ethoxycarbonylfuryl)methanephosphonates under conditions of the Claisen reaction. H-1, C-13, and P-31 NMR spectroscopy studies have shown that the products exist as equilibrium mixtures of the carbonyl compounds and its E- and Z-enol forms in chloroform solutions. Acylation of these substances with diethyl chlorophosphate has yielded the corresponding enol phosphates. Influence of the substituents location in the furan ring on predominance of cis- or trans-configuration has been demonstrated.

  DOI：

  10.1134/s1070363214110188