2-(1,1-Dimethylethyl)-5-(4-piperidinyl)pyridine | 1211533-47-9

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: 2-(1,1-Dimethylethyl)-5-(4-piperidinyl)pyridine
• 英文别名: 2-tert-butyl-5-piperidin-4-ylpyridine
• CAS: 1211533-47-9
• 化学式: C₁₄H₂₂N₂
• 分子量: 218.34
• InChiKey: ROXKBTLAYCGISY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.7
• 重原子数：
  16
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.64
• 拓扑面积：
  24.9
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• PHOSPHOROUS DERIVATIVES AS KINASE INHIBITORS
  申请人：ARIAD PHARMACEUTICALS, INC.

  公开号：US20150225436A1

  公开（公告）日：2015-08-13

  The invention features compounds of the general formula: in which the variable groups are as defined herein, and to their preparation and use.

  该发明涉及一般式化合物：其中变量基团如本文所定义，以及它们的制备和使用。
• PHOSPHORUS DERIVATIVES AS KINASE INHIBITORS
  申请人：Wang Yihan

  公开号：US20120202776A1

  公开（公告）日：2012-08-09

  The invention features compounds of the general formula (I) in which the variable groups are as defined herein, and to their preparation and use.

  该发明涉及通式（I）中变量基团如此定义的化合物，以及它们的制备和使用。
• Phosphorus Derivatives as Kinase Inhibitors
  申请人：ARIAD PHARMACEUTICALS, INC.

  公开号：US20130225527A1

  公开（公告）日：2013-08-29

  The invention features compounds of the general formula: in which the variable groups are as defined herein, and to their preparation and use.

  本发明涉及一般式化合物：其中变量基团的定义如本文所述，以及其制备和使用。
• Phosphorous Derivatives as Kinase Inhibitors
  申请人：ARIAD Pharmaceuticals, Inc.

  公开号：US20160376297A1

  公开（公告）日：2016-12-29

  The invention features compounds of the general formula: in which the variable groups are as defined herein, and to their preparation and use.

  本发明涉及一般式化合物：其中变量基团如此定义，以及它们的制备和使用。
• PYRAZINOPYRAZINES AND DERIVATIVES AS KINASE INHIBITORS
  申请人：Huang Wei-Sheng

  公开号：US20110288078A1

  公开（公告）日：2011-11-24

  This invention relates to compounds of the general formula: in which the variable groups are as defined herein, and to their preparation and use.

  本发明涉及以下通式的化合物：其中变量基团如本文所定义，以及它们的制备和使用。