| 130762-44-6

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 二苯乙烯类
• CAS: 130762-44-6
• 化学式: C₂₇H₃₁N₃O₃
• 分子量: 447.563
• InChiKey: WYGBQUHHJFCULZ-MISLCCGRSA-N

反应信息

• 作为产物：
  描述：

  4-benzoyl-5-phenyl(117O)furan-2,3-dione 、 N,N'-二异丙基碳二亚胺 反应 16.0h， 生成
  参考文献：
  名称：

  Mechanistic investigations aided by isotopic labeling. 10. Investigations of novel furan-2,3-dione rearrangements by oxygen-17 labeling

  摘要：

  The oxa 1,3-diene moiety in 4-benzoyl-5-phenylfuran-2,3-dione (1) adds aryl isocyanides or heterocumulenes via formal [4 + 1] or [4 + 2] cycloaddition processes. The unstable primary adducts undergo novel furandione rearrangements to intermediates in which the two oxygen atoms of the lactone moiety in 1 are equivalent. This equivalence was confirmed by O-17-labeling experiments using O-17 NMR spectroscopic and mass spectroscopic measurements. Comparison of the O-17 chemical shifts in 1, labeled either at the benzoyl and ring oxygens (1a-O-17) or at both exocyclic ring-carbonyl oxygens (1b-O-17), with those in the products 2-4 confirmed the proposed pathways of these rearrangements. Reactions involving carbodiimides, isocyanates, and ketene imines were investigated.

  DOI：

  10.1021/jo00001a044