2-hydroxyl-3-nitro-benzaldehyde 4'-nitrophenylhydrazone | 710333-52-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 酚类
• 英文名称: 2-hydroxyl-3-nitro-benzaldehyde 4'-nitrophenylhydrazone
• 英文别名: 2-Nitro-6-[[(4-nitrophenyl)hydrazinylidene]methyl]phenol
• CAS: 710333-52-1
• 化学式: C₁₃H₁₀N₄O₅
• 分子量: 302.246
• InChiKey: UMVNXCZRVFYWPS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.4
• 重原子数：
  22
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  136
• 氢给体数：
  2
• 氢受体数：
  7

反应信息

• 作为产物：
  描述：

  3-硝基水杨醛 、 4-硝基苯肼 以 乙醇 为溶剂， 反应 1.0h， 以92%的产率得到2-hydroxyl-3-nitro-benzaldehyde 4'-nitrophenylhydrazone
  参考文献：
  名称：

  A high selective anion colorimetric sensor based on salicylaldehyde for fluoride in aqueous media

  摘要：

  A new and simple salicylaldehyde-based sensor 1 designed for fluoride sensing has been investigated in DMSO and even in the 9/1 DMSO/H2O (v/v) Mixtures. The affinity constants of receptor 1 for anionic species in the 9/1 DMSO/H2O (v/v) reveal that it is sensitive to F. Also, the color changes induced by anions can provide a way of detection by 'naked-eye'. These result can be substantiated by the spectrum changes upon the addition of 25 equiv. anions to 1 in the 9/1 DMSO/H2O solution. The further insights to the nature of interactions between the sensor 1and F were investigated by H-1 NMR titration experiments in 9/1 DMSO-d(6)/H2O (v/v). In addition, the proposed binding mode between 1 and F- was suggested. (C) 2009 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.saa.2008.12.045