N-methyl-N-butylhexylamine | 41781-45-7

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: N-methyl-N-butylhexylamine
• 英文别名: N-butyl-N-methylhexan-1-amine
• CAS: 41781-45-7
• 化学式: C₁₁H₂₅N
• 分子量: 171.326
• InChiKey: VJZIQTSOTIRPLZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.8
• 重原子数：
  12
• 可旋转键数：
  8
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  3.2
• 氢给体数：
  0
• 氢受体数：
  1

文献信息

• [EN] METHOD FOR PREPARATION OF CYANO COMPOUNDS OF BORON WITH A BRONSTEDT ACID<br/>[FR] PROCÉDÉ DE PRÉPARATION DE COMPOSÉS CYANO DE BORE AVEC UN ACIDE DE BRONSTEDT
  申请人：LONZA AG

  公开号：WO2016162400A1

  公开（公告）日：2016-10-13

  The invention discloses a method for preparation of cyano compounds of boron with 1, 2, 3 or 4 cyano residues, represented by formula (I): [Catn+] [(BF4-m(CN)m)- ]n by a reaction of compound of formula (A1) with trimethylsilylcyanide in the presence of a Bronstedt acid; [Catn+] [(BF4)- ]n (A1); n+ Cat is a cation, m is 1, 2, 3 or 4 and n is 1, 2, 3 or 4. In a specific embodiment, the method is for prepration of the following three compounds: [(n-Bu)4N][BF(CN)3] (1), [(n-Pr)3NH][BF(CN)3] (2), [(n-Pr)3NH][B(CN)4] (3).

  该发明揭示了一种制备具有1、2、3或4个氰基的硼氰化合物的方法，其表示为公式（I）：[Catn+] [(BF4-m(CN)m)- ]n，通过化合物公式（A1）与三甲基硅基氰化物在布朗斯特酸存在下的反应实现；[Catn+] [( )- ]n（A1）；n+ Cat为阳离子，m为1、2、3或4，n为1、2、3或4。在特定实施例中，该方法用于制备以下三种化合物：[(n-Bu)4N][BF(CN)3]（1）、[(n-Pr)3NH][BF(CN)3]（2）、[(n-Pr)3NH][B(CN)4]（3）。
• Amine oxide process and composition
  申请人：ETHYL CORPORATION

  公开号：EP0230510A2

  公开（公告）日：1987-08-05

  A highly concentrated aqueous solution of a di-C6-20 alkyl methylamine oxide containing at least 50 weight percent of the amine oxide can be made without gel formation by reacting at least 40 weight percent aqueous hydrogen peroxide with a di-C6-20 alkyl methyl or ethylamine. These concentrated solutions offer large freight savings in shipping the amine oxides to remote locations.

  通过将至少 40% 的过氧化氢水溶液与二-C6-20 烷基甲基或乙基胺反应，可制成含至少 50% 氧化胺的高浓度二-C6-20 烷基甲胺水溶液，而不会形成凝胶。将这些浓缩溶液运送到偏远地区可节省大量运费。
• VASOPRESSIN ANTAGONIST AND OXYTOCIN ANTAGONIST
  申请人：OTSUKA PHARMACEUTICAL CO., LTD.

  公开号：EP0620003A1

  公开（公告）日：1994-10-19

  A benzazepine compound represented by formulae (I) or (II) or a salt thereof, and a vasopressin antagonist or an oxytocin antagonist containing the above compound as the active ingredient.

  由式（I）或（II）代表的苯并氮杂卓化合物或其盐，以及含有上述化合物作为活性成分的血管加压素拮抗剂或催产素拮抗剂。
• Novel quaternary ammonium salt and process for the preparation thereof
  申请人：TOAGOSEI CO., LTD.

  公开号：EP1156030A1

  公开（公告）日：2001-11-21

  The novel quaternary ammonium salt according to the invention has two quaternary ammonium groups connected to a benzene ring, wherein two C4-12 alkyl groups and one C1-2 alkyl group are connected per one nitrogen atom constituting the quaternary ammonium. The compound is used as an antimicrobial agent, exhibits a high safety to human as compared with known antimicrobial agents, exerts an excellent sterilizing effect itself and exhibits a wide sterilizing spectrum. In particular, the compound is used as a presevative for eye drop.

  根据本发明的新型季铵盐具有两个与苯环相连的季铵基团，其中构成季铵的每一个氮原子连接两个 C4-12 烷基和一个 C1-2 烷基。该化合物可用作抗菌剂，与已知的抗菌剂相比，对人体具有较高的安全性，本身具有极佳的杀菌效果，杀菌谱广。特别是，该化合物可用作滴眼液的前处理剂。
• Vasopressin antagonist and oxytocin antagonist
  申请人：Otsuka Pharmaceutical Company, Limited

  公开号：EP1902717A2

  公开（公告）日：2008-03-26

  An object of the present invention is to provide a vasopressin antagonist and oxytocin antagonist. The vasopressing antagonist and oxytocin antagonist according to the present invention contain, as the active ingredient, a benzoheterocyclic compound represented by the general formula (1): (wherein R1, R2, R3, R4, R5 and the carbon-carbon bond between 4- and 5-positions in the benzoazepine skeleton are the same as defined in Claims 1 and 2) or salt thereof.

  本发明的目的是提供一种血管加压素拮抗剂和催产素拮抗剂。 根据本发明，血管加压素拮抗剂和催产素拮抗剂含有通式（1）所代表的苯并杂环化合物作为活性成分： (其中 R1、R2、R3、R4、R5 和苯并氮杂卓骨架中 4 位和 5 位之间的碳-碳键与权利要求 1 和 2 中定义的相同）或其盐。