1-[[2-(Propylamino)ethyl]amino]-2-propanol | 1211480-01-1

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: 1-[[2-(Propylamino)ethyl]amino]-2-propanol
• 英文别名: 1-[2-(propylamino)ethylamino]propan-2-ol
• CAS: 1211480-01-1
• 化学式: C₈H₂₀N₂O
• 分子量: 160.26
• InChiKey: ZURZWXRECFZDEV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0
• 重原子数：
  11
• 可旋转键数：
  7
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  44.3
• 氢给体数：
  3
• 氢受体数：
  3

文献信息

• TARGETED CONTRAST AGENTS FOR MRI OF AMYLOID DEPOSITION
  申请人：Texas Children's Hospital

  公开号：US20210236662A1

  公开（公告）日：2021-08-05

  A liposomal composition (“ADx-001”) is provided, ADx-001 comprising a first phospholipid; a sterically bulky excipient that is capable of stabilizing the liposomal composition; a second phospholipid that is derivatized with a first polymer; a macrocyclic gadolinium-based imaging agent; and a third phospholipid that is derivatized with a second polymer, the second polymer being conjugated to a targeting ligand. The macrocyclic gadolinium-based imaging agent may be conjugated to a fourth phospholipid.