Tetradecyl-isobutyl-amin | 36555-71-2

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: Tetradecyl-isobutyl-amin
• 英文别名: N-(2-Methylpropyl)tetradecan-1-amine
• CAS: 36555-71-2
• 化学式: C₁₈H₃₉N
• 分子量: 269.514
• InChiKey: MXMYGTUQFYBDRX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.8
• 重原子数：
  19
• 可旋转键数：
  15
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  12
• 氢给体数：
  1
• 氢受体数：
  1

文献信息

• [EN] PERSONAL CARE COMPOSITIONS COMPRISING FATTY ACID AMIDE DERIVATIVES<br/>[FR] COMPOSITIONS DE SOIN PERSONNEL COMPRENANT DES DÉRIVÉS D'AMIDES D'ACIDE GRAS
  申请人：UNILEVER PLC

  公开号：WO2018019463A1

  公开（公告）日：2018-02-01

  In one embodiment, the present invention provides a personal care composition, comprising: (i) a compound of Formula (1) at a concentration from 0.0001 wt % to 20 wt % of the composition; wherein R is selected from the group consisting of C15-C23 conjugated dienes, C15-C23 hydroxylated mono unsaturated alkenes, and C15-C23 hydroxylated alkanes; wherein R1 is selected from the group consisting of H, C1-C4 alkyl, - CH2OH, -CH2(CH3)-OH,-[CH2]4-NH2, -CH2-CO2H, -[CH2]2-CO2H, (I), (II) and (III); wherein R3 is -CO2H; -CH2CO2H; -CH2CH2CO2H;; and (ii) a cosmetically acceptable carrier.

  在一个实施例中，本发明提供一种个人护理组合物，包括：(i) 按照浓度为0.0001重量%至20重量%的组合物的公式(1)的化合物；其中R从C15-C23共轭二烯烃、C15-C23羟基单不饱和烯烃和C15-C23羟基烷烃组成的群体中选择；其中R1从H、C1-C4烷基、- CH2OH、-CH2(CH3)-OH、-[CH2]4-NH2、-CH2-CO2H、-[CH2]2-CO2H、(I)、(II)和(III)组成的群体中选择；其中R3为-CO2H；-CH2CO2H；-CH2CH2CO2H；；和(ii) 一种化妆品可接受的载体。
• Diaz(ep)ine bis(N-amidinoamidine) derivatives
  申请人：IMPERIAL CHEMICAL INDUSTRIES PLC

  公开号：EP0125093A1

  公开（公告）日：1984-11-14

  A diaz(ep)ine bis(N-amidinoamidine) derivative of the formula:- or a tautomeric form thereof, wherein R10, R", R12. R13, R", R15, R16 and R17, which may be the same or different, are each hydrogen, a 1-16C alkyl radical, a 3-18C cycloalkyl or cycloalkylalkyl radical, or an optionally-substituted phenyl (1-4C alkyl) radical, or R'°, R" and the nitrogen atom to which they are attached, or R12 and R" and the nitrogen atom to which they are attached, or R14 and R15 and the nitrogen atom to which they are attached, or R16 and R17 and the nitrogen atom to which they are attached, which may be the same or different, are each a 1-azetidinyl, 1-pyrrolidinyl, piperidino, hexamethyleneimino, heptamethyleneimino, morpholino or 4-(1-8C alkanoyl)-1-piperazinyl radical, or R10 and R14 together with the two nitrogen atoms to which they are attached and the intervening carbon atom, or R12 and R16 together with the two nitrogen atoms to which they are attached and the intervening carbon atom, each forms a 1,3-diazaheterocyclic radical of 5 to 7 atoms, which heterocyclic radicals may be the same or different; and m is 2 or 3; provided that R'°, R", R12, R13, R14, R'5, R" and R17 togethercontain 16to 28 carbon atoms, and the acid addition salts thereof, processes for their manufacture and antibacterial and antifungal compositions and methods using said compounds.

  式中的重氮(表)烯双(N-脒基脒)衍生物 或其同分异构体，其中 R10、R"、R12.R13、R"、R15、R16 和 R17（可以相同或不同）各自为氢、1-16C 烷基、3-18C 环烷基或环烷基烷基、或任选取代的苯基（1-4C 烷基）基，或 R'°、R "和它们所连接的氮原子、或 R12 和 R "及其所连接的氮原子，或 R14 和 R15 及其所连接的氮原子，或 R16 和 R17 及其所连接的氮原子，它们可以相同或不同、各自是 1-氮杂环丁基、1-吡咯烷基、哌啶基、六亚甲基亚氨基、七亚甲基亚氨基、吗啉基或 4-（1-8C 烷酰基）-1-哌嗪基，或 R10 和 R14 连同它们所连接的两个氮原子和中间的碳原子、或 R12 和 R16 与它们所连接的两个氮原子和中间的碳原子一起，各自形成 5 至 7 个原子的 1，3-二氮杂环基，这些杂环基可以相同或不同；m为2或3；条件是R'°、R"、R12、R13、R14、R'5、R "和R17一起含有16至28个碳原子，以及它们的酸加成盐、它们的制造工艺和使用所述化合物的抗菌和抗真菌组合物和方法。