2-(N-dodecyl-anilino)-ethanesulfonic acid | 7582-46-9

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: 2-(N-dodecyl-anilino)-ethanesulfonic acid
• 英文别名: N-Dodecyl-N-phenyl-taurin；2-(N-Dodecyl-anilino)-aethansulfonsaeure
• CAS: 7582-46-9
• 化学式: C₂₀H₃₅NO₃S
• 分子量: 369.569
• InChiKey: DCQFGTDCHNJNFP-UHFFFAOYSA-N

反应信息

• 作为产物：
  描述：

  溴代十二烷 、 alkaline earth salt of/the/ methylsulfuric acid 在 乙醇 、 potassium iodide 作用下， 生成 2-(N-dodecyl-anilino)-ethanesulfonic acid
  参考文献：
  名称：

  Malignant Pericardial Effusion

  摘要：

  OBJECTIVE: To examine the frequency and diagnostic implications of malignant pericardial effusions.STUDY DESIGN: The clinical and histologic records of pericardial effusions diagnosed cytologically as malignant were reviewed. We investigated the relationship between malignancy and type of tumor, interval between diagnosis of the primary tumor and development of the pericardial effusion, and length of survival after the onset of the effusion.RESULTS: There were 375 pericardial effusions among 23,592 effusions studied over 24 years; 65 of them were diagnosed as malignant. The mean age at onset was 53.6 years. In 92% of the cases the primary tumor was epithelial, lung the most frequent in males and breast in females. In 48% of cases the pericardial effusion constituted the first sign of malignancy.CONCLUSION: Diagnosis of a pericardial effusion as malignant carried an ominous prognosis: 86% of patients died within the first year and nearly one-third within the first month. Breast carcinomas were linked with the longest survival and longest interval of latency prior to the onset of the pericardial effusion. There were two effusions associated with lymphoblastic lymphomas; they have had no recurrence 10 and 17 years after the effusion, and the patients can be considered cured.

  DOI：

  10.1159/000327865