5-({[(Tert-butoxy)carbonyl]amino}methyl)furan-3-carboxylic acid | 1797772-60-1

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 呋喃
• 英文名称: 5-({[(Tert-butoxy)carbonyl]amino}methyl)furan-3-carboxylic acid
• 英文别名: 5-[[(2-methylpropan-2-yl)oxycarbonylamino]methyl]furan-3-carboxylic acid
• CAS: 1797772-60-1
• 化学式: C₁₁H₁₅NO₅
• mdl: MFCD27980629
• 分子量: 241.24
• InChiKey: YVYPMRKEKXLHID-UHFFFAOYSA-N

物化性质

• 沸点：
  415.3±40.0 °C(Predicted)
• 密度：
  1.231±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1.1
• 重原子数：
  17
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.454
• 拓扑面积：
  88.8
• 氢给体数：
  2
• 氢受体数：
  5

文献信息

• LONG CHAIN CARBON AND CYCLIC AMINO ACIDS SUBSTRATES FOR GENETIC CODE REPROGRAMMING
  申请人：Northwestern University

  公开号：EP4103734A2

  公开（公告）日：2022-12-21
• Expanding the Chemical Substrates for Genetic Code Reprogramming
  申请人：Northwestern University

  公开号：US20210230586A1

  公开（公告）日：2021-07-29

  Disclosed are methods, systems, components, and compositions for synthesis of sequence defined polymers. The methods, systems, components, and compositions may be utilized for incorporating novel substrates that include non-standard amino acid monomers and non-amino acid monomers into sequence defined polymers. As disclosed herein, the novel substrates may be utilized for acylation of tRNA via flexizyme catalyzed reactions. The tRNAs thus acylated with the novel substrates may be utilized in synthesis platforms for incorporating the novel substrates into a sequence defined polymer.
• [EN] EXPANDING THE CHEMICAL SUBSTRATES FOR GENETIC CODE REPROGRAMMING<br/>[FR] EXPANSION DE SUBSTRATS CHIMIQUES POUR LA REPROGRAMMATION DU CODE GÉNÉTIQUE
  申请人：UNIV NORTHWESTERN

  公开号：WO2020040840A2

  公开（公告）日：2020-02-27

  Disclosed are methods, systems, components, and compositions for synthesis of sequence defined polymers. The methods, systems, components, and compositions may be utilized for incorporating novel substrates that include non-standard amino acid monomers and non-amino acid monomers into sequence defined polymers. As disclosed herein, the novel substrates may be utilized for acylation of tRNA via flexizyme catalyzed reactions. The tRNAs thus acylated with the novel substrates may be utilized in synthesis platforms for incorporating the novel substrates into a sequence defined polymer.
• [EN] EXPANDING THE CHEMICAL SUBSTRATES FOR GENETIC CODE REPROGRAMMING TO INCLUDE LONG CHAIN CARBON AND CYCLIC AMINO ACIDS<br/>[FR] DÉVELOPPEMENT DES SUBSTRATS CHIMIQUES DE REPROGRAMMATION DE CODE GÉNÉTIQUE POUR QU'ILS COMPRENNENT DU CARBONE À LONGUE CHAÎNE ET DES ACIDES AMINÉS CYCLIQUES
  申请人：UNIV NORTHWESTERN

  公开号：WO2021221760A2

  公开（公告）日：2021-11-04

  Disclosed are methods, systems, components, and compositions for synthesis of sequence defined polymers. The methods, systems, components, and compositions may be utilized for incorporating novel substrates that include non-standard amino acid monomers and non-amino acid monomers into sequence defined polymers. As disclosed herein, the novel substrates may be utilized for acylation of tRNA via flexizyme catalyzed reactions. The tRNAs thus acylated with the novel substrates may be utilized in synthesis platforms for incorporating the novel substrates into a sequence defined polymer.