摩熵化学
数据库官网
小程序
打开微信扫一扫
首页 分子通 化学资讯 化学百科 反应查询 关于我们
请输入关键词

2-(4-butoxy-5H-chromeno[2,3-d]pyrimidin-2-yl)phenol | 1430823-16-7

中文名称
——
中文别名
——
英文名称
2-(4-butoxy-5H-chromeno[2,3-d]pyrimidin-2-yl)phenol
英文别名
2-(4,9-dimethoxy-5H-chromeno[2,3-d]pyrimidin-2-yl)phenol
2-(4-butoxy-5H-chromeno[2,3-d]pyrimidin-2-yl)phenol化学式
CAS
1430823-16-7
化学式
C19H16N2O4
mdl
——
分子量
336.347
InChiKey
OEVMVYPPJNOTLF-UHFFFAOYSA-N
BEILSTEIN
——
EINECS
——
  • 物化性质
  • 计算性质
  • ADMET
  • 安全信息
  • SDS
  • 制备方法与用途
  • 上下游信息
  • 反应信息
  • 文献信息
  • 表征谱图
  • 同类化合物
  • 相关功能分类
  • 相关结构分类

计算性质

  • 辛醇/水分配系数(LogP):
    3.6
  • 重原子数:
    25
  • 可旋转键数:
    3
  • 环数:
    4.0
  • sp3杂化的碳原子比例:
    0.16
  • 拓扑面积:
    73.7
  • 氢给体数:
    1
  • 氢受体数:
    6

反应信息

  • 作为产物:
    描述:
    邻香草醛三乙胺 作用下, 以 乙醇 为溶剂, 反应 0.67h, 生成 2-(4-butoxy-5H-chromeno[2,3-d]pyrimidin-2-yl)phenol
    参考文献:
    名称:
    Efficient and Ecofriendly Route for the Solvent-Free Synthesis of 4-Alkoxy-5H-chromen[2,3-d]pyrimidines Using Phosphonic Acid Functionalized KIT-6 Confined Ionic Liquid as Recoverable Catalyst
    摘要:
    DOI:
    10.1080/00397911.2014.916722
点击查看最新优质反应信息

文献信息

  • Novel Approaches for the Synthesis of a Library of Fluorescent Chromenopyrimidine Derivatives
    作者:Afsaneh Zonouzi、Fatemeh Hosseinzadeh、Nastaran Karimi、Roghieh Mirzazadeh、Seik Weng Ng
    DOI:10.1021/co300141j
    日期:2013.5.13
    A library of some new fluorescent chromenopyrimidine derivatives has been synthesized by new approaches. Water-promoted and one-pot reaction can produce new dialkylylamino)-5H-chromeno[2,3-d]pyrimidin-2-yl) phenols. These compounds can also be produced using domino reaction. Two parallel methods are compared. Novel N-alkyl-N-phenyl-5H-chromeno [2,3-d] -pyrimidin-4-amines and 4-alkoxy-5H-chromeno[2, 3-d]pyrimidines are synthesized by Lewis-acid catalyzed reactions. The fluorescence emission intensity of the four compounds from each of libraries after excitation in 290 nm is measured. Compound 2-(4,5-bis(N-methyl-N-phenylamino)-5H-chromeno[2,3-d]pyrimidin-2-yl)phenol was isolated as a byproduct. The details of an interesting exchangeable intramolecular H-bonding of two of the new compounds are reported by X-ray analysis data.
查看更多