4-{[2-(Dimethylamino)ethyl](methyl)amino}cyclohexan-1-one | 1529158-02-8

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: 4-{[2-(Dimethylamino)ethyl](methyl)amino}cyclohexan-1-one
• 英文别名: 4-[2-(dimethylamino)ethyl-methylamino]cyclohexan-1-one
• CAS: 1529158-02-8
• 化学式: C₁₁H₂₂N₂O
• 分子量: 198.31
• InChiKey: RXOOHWWWEUJXME-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.5
• 重原子数：
  14
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.91
• 拓扑面积：
  23.6
• 氢给体数：
  0
• 氢受体数：
  3

文献信息

• 4,5,6-TRI-SUBSTITUTED INDAZOLES DERIVATIVES, PREPARATION THEREOF, AND USE THEREOF IN MEDICINES
  申请人：Shanghai Haiyan Pharmaceutical Technology Co., Ltd.

  公开号：EP3441388A1

  公开（公告）日：2019-02-13

  Provided are 4,5,6-tri-substituted indazoles derivatives, a preparation method therefor, and a use thereof in medicines. Specifically, provided are compounds of formula (I) or pharmaceutically acceptable salts, stereoisomers, solvates, or prodrugs thereof, a preparation method therefor, and a use thereof.

  提供了4,5,6-三取代吲唑衍生物，其制备方法以及在药物中的用途。具体来说，提供了式（I）化合物或药用可接受的盐、立体异构体、溶剂合物或前药，其制备方法以及在药物中的用途。
• 4, 5, 6-TRI-SUBSTITUTED INDAZOLES DERIVATIVES, PREPARATION THEREOF AND USE THEREOF IN MEDICINES
  申请人：SHANGHAI HAIYAN PHARMACEUTICAL TECHNOLOGY CO., LTD.

  公开号：US20200262812A1

  公开（公告）日：2020-08-20

  Provided are 4,5,6-tri-substituted indazoles derivatives, a preparation method therefor, and a use thereof in medicines. Specifically, provided are compounds of formula (I) or pharmaceutically acceptable salts, stereoisomers, solvates, or prodrugs thereof, a preparation method therefor, and a use thereof.