4,4'-二叠氮基联苯 | 2915-43-7

• 分子结构分类: 有机化合物 - 有机氮化合物
• 中文名称: 4,4'-二叠氮基联苯
• 英文名称: 4,4'-diazidobiphenyl
• 英文别名: 4,4'-Diazidodiphenyl；[[4-(4-diazonioiminocyclohexa-2,5-dien-1-ylidene)cyclohexa-2,5-dien-1-ylidene]hydrazinylidene]azanide
• CAS: 2915-43-7
• 化学式: C₁₂H₈N₆
• 分子量: 236.236
• InChiKey: XUGUHTGSMPZQIW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.7
• 重原子数：
  18
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  66.2
• 氢给体数：
  0
• 氢受体数：
  5

安全信息

• 海关编码：
  2929909090

反应信息

• 作为反应物：
  描述：

  4,4'-二叠氮基联苯 在 sodium hydrogensulfide 作用下， 以 乙醇 、 水 为溶剂， 反应 0.5h， 以11%的产率得到4'-amino-4-azidobiphenyl
  参考文献：
  名称：

  Photochemical Reactions of Nitroso Oxides at Low Temperatures:  The First Experimental Evidence for Dioxaziridines

  摘要：

  Several singlet nitroso oxides (3a-e) were generated by the thermal reaction of triplet nitrenes (2a-e) with triplet oxygen at. 95 K in 2-methyltetrahydrofuran. After photolysis of the nitroso oxides at 77 K using strong light intensities, the formation of intermediates was observed for the first rime. From spectroscopic, kinetic, and chemical arguments, we postulate the formation of the following dioxaziridines: 4-(dioxaziridin-yl)stilbene (4a), 4-(dioxaziridin-yl)-4'-nitrostilbene (4b), 4'-(dioxaziridin-yl)-4-(dimethylamino)st (4c), 4'-(dioxaziridin-yl)-4-aminobiphenyl (4d), and 4-(dioxaziridin-yl)-4'-(nitrene-substituted)stilbene (4f). All dioxaziridines observed are highly reactive species. At 77 K, they react thermally to form the corresponding nitro compounds (5). The velocity of the ring opening reaction of the dioxaziridines (4 --> 5) is not significantly influenced by substituents; the rate constants at 77 K are all equal to 0.0030 +/- 0.0005 s(-1). The transients were characterized by stationary UV/vis and/or ESR spectroscopy. Ab initio calculations of the thermal reaction of the nonsubstituted dioxaziridine (6) and N-phenyldioxaziridine (9) were performed. From this, it follows that dioxaziridines are experimentally observable species which are separated from the corresponding nitro products by an orbital symmetry-forbidden barrier.

  DOI：

  10.1021/ja9803660
• 作为产物：
  描述：

  联苯胺 在 盐酸 、 sodium nitrite 、 sodium azide 作用下， 以 水 为溶剂， 以78.1 %的产率得到4,4'-二叠氮基联苯
  参考文献：
  名称：

  用三唑基螯合物构建多核发光镧系元素有机多面体的细微调整

  摘要：

  预定的多核镧系元素有机多面体 （LOP） 的受控自组装仍然是一个挑战，主要是由于镧系元素离子的配位数不可预测和配位几何形状不稳定。在本研究中，通过引入基于三唑的螯合物来增加 C2 对称线性配体的螯合角并稳定 Eu（III） 中心的配位几何形状，有效地合成了 M4L6 型 （M = EuIII， L = 配体） 四面体，尤其是众所周知形成 M2L3 的联苯桥配体-类型的螺旋。形成一系列 LOP，并通过高分辨率电喷雾电离飞行时间质谱 （ESI-TOF-MS） 和 X 射线晶体学表征。此外，铕配合物表现出明亮的发射（发光量子产率高达 42.4%）和圆偏振发光特性 （|glum|最高 4.5 × 10−2）。本研究为构建多核发光 LOPs 提供了一种可行的策略，以用于潜在应用。

  DOI：

  10.1039/d3dt03791f

文献信息

• BASIC COMPOUND, CHEMICALLY AMPLIFIED RESIST COMPOSITION, AND PATTERNING PROCESS
  申请人：Hatakeyama Jun

  公开号：US20120141938A1

  公开（公告）日：2012-06-07

  A chemically amplified resist composition comprising a base polymer, an acid generator, and an amine quencher in the form of a β-alanine, γ-aminobutyric acid or 5-aminovaleric acid derivative having an acid labile group-substituted carboxyl group has a high contrast of alkaline dissolution rate before and after exposure and forms a pattern of good profile at a high resolution, minimal roughness and wide focus margin.

  一种化学放大型光刻胶组合物，包括基础聚合物、酸发生剂和胺淬灭剂，后者为β-丙氨酸、γ-氨基丁酸或5-氨基戊酸的衍生物，具有一个被酸不稳定基团所取代的羧基，这种组合物在曝光前后具有高对比度的碱性溶解速率，并且能够形成高分辨率、最小粗糙度和宽焦深度的良好图案轮廓。
• Characterizing Triplet States of Quinonoidal Dinitrenes as a Function of Conjugation Length
  作者：Masaki Minato、Paul M. Lahti

  DOI：10.1021/ja963648d

  日期：1997.3.1

  Photolysis of para,para‘-diazide precursors in 2-methyltetrahydrofuran gives biradical ESR spectra assignable to quinonoidal dinitrenes with excited triplet biradical states. The zero field splitting (zfs) parameters for the biradicals at 77 K are as follows: 1,4-phenylenedinitrene (|D/hc| = 0.169 cm-1, |E/hc| = 0.004 cm-1); 4,4‘-biphenyldinitrene (|D/hc| = 0.188 cm-1, |E/hc| ≤ 0.002 cm-1); 4,4‘-stilbenedinitrene

  对，对'-二叠氮前体在 2-甲基四氢呋喃中的光解得到双自由基 ESR 光谱，可归属于具有激发三重双自由基状态的醌型二硝烯。77 K 双自由基的零场分裂 (zfs) 参数如下： 1,4-亚苯基二烯 (|D/hc| = 0.169 cm-1, |E/hc| = 0.004 cm-1)；4,4'-联苯二甲苯（|D/hc| = 0.188 cm-1，|E/hc| ≤ 0.002 cm-1）；4,4'-二苯乙烯二烯（|D/hc| = 0.122 cm-1，|E/hc| < 0.002 cm-1）；1,4-双（对硝基苯）丁-1,3-二烯（|D/hc| = 0.0865 cm-1，|E/hc| < 0.002 cm-1）；1,8-双（对硝基苯）八-1,3,5,7-四烯（|D/hc| = 0.0442 cm-1，|E/hc| < 0.001 cm-1）。这些 zfs 参数与局部双自由基中 ESR 光谱的简
• NOVOLAC RESIN AND RESIST FILM
  申请人：DIC Corporation

  公开号：US20180334523A1

  公开（公告）日：2018-11-22

  Provided are a novolac resin having developability, heat resistance, and dry etching resistance, and a photosensitive composition, a curable composition, and a resist film. A novolac resin including, as a repeating unit, a structural moiety represented by Structural Formula (1) or (2): (in the formula, Ar represents an arylene group, R 1 's each independently represent any one of a hydrogen atom, an alkyl group, an alkoxy group, and a halogen atom, m's each independently represent an integer of 1 to 3, and X is any one of a hydrogen atom, a tertiary alkyl group, an alkoxyalkyl group, an acyl group, an alkoxycarbonyl group, a hetero atom-containing cyclic hydrocarbon group, and a trialkylsilyl group) in which at least one of X's present in the resin is any one of a tertiary alkyl group, an alkoxyalkyl group, an acyl group, an alkoxycarbonyl group, a hetero atom-containing cyclic hydrocarbon group, and a trialkylsilyl group.

  提供一种具有可开发性、耐热性和干法蚀刻抗性的新戊醛树脂，以及一种光敏组合物、可固化组合物和抗蚀膜。一种新戊醛树脂包括以下结构单元： （在公式中，Ar代表芳基，R 1 分别独立地代表氢原子、烷基、烷氧基和卤素原子中的任意一种，m分别独立地代表1至3的整数，X代表氢原子、三级烷基、烷氧基烷基、酰基、烷氧羰基、含杂原子的环烃基和三烷基硅基中的任意一种），树脂中至少有一个X是三级烷基、烷氧基烷基、酰基、烷氧羰基、含杂原子的环烃基和三烷基硅基中的任意一种。
• [EN] PNEUMOCOCCAL POLYSACCHARIDE-PROTEIN CONJUGATE COMPOSITION<br/>[FR] COMPOSITION DE CONJUGUÉ POLYSACCHARIDE PNEUMOCOCCIQUE-PROTÉINE
  申请人：MAX-PLANCK-GESELLSCHAFT ZUR FÖRDERUNG DER WSS E V

  公开号：WO2017220753A1

  公开（公告）日：2017-12-28

  The present invention relates to immunogenic compositions comprising a conjugate of a saccharide from Streptococcus pneumoniae serotype 8 and a carrier protein, and a mixture consisting of capsular polysaccharides from Streptococcus pneumoniae serotypes 1, 3, 4, 5, 6A, 6B, 7F, 9V, 14, 18C, 19A, 19F and 23F individually conjugated to CRM197 carrier protein, or a mixture consisting of capsular polysaccharides from Streptococcus pneumoniae serotypes 1, 4, 5, 6B, 7F, 9V, 14, 18C, 19F and 23F individually conjugated to a carrier protein, wherein the capsular polysaccharides from Streptococcus pneumoniae serotypes 1, 4, 5, 6B, 7F, 9V, 14, and 23F are individually conjugated to protein D, the capsular polysaccharide from Streptococcus pneumoniae serotype 18C is conjugated to tetanus toxoid and the capsular polysaccharide from Streptococcus pneumoniae serotype 19F is conjugated to diphtheria toxoid. Said compositions are useful for the prevention and/or treatment of diseases caused by Streptococcus pneumoniae.

  本发明涉及包含链球菌肺炎8型的糖类与载体蛋白的结合物的免疫原组合物，以及由链球菌肺炎1、3、4、5、6A、6B、7F、9V、14、18C、19A、19F和23F型的胶囊多糖组成的混合物，分别与CRM197载体蛋白共轭，或由链球菌肺炎1、4、5、6B、7F、9V、14、18C、19F和23F型的胶囊多糖组成的混合物，分别与载体蛋白共轭，其中链球菌肺炎1、4、5、6B、7F、9V、14和23F型的胶囊多糖分别与蛋白D共轭，链球菌肺炎18C型的胶囊多糖与破伤风类毒素结合，链球菌肺炎19F型的胶囊多糖与白喉类毒素结合。该组合物对预防和/或治疗由链球菌肺炎引起的疾病有用。
• Rh(III)-Catalyzed C–H Activation of Boronic Acid with Aryl Azide
  作者：Shiyang Xu、Baoliang Huang、Guanyu Qiao、Ziyue Huang、Zhen Zhang、Zongyang Li、Peng Wang、Zhenhua Zhang

  DOI：10.1021/acs.orglett.8b02247

  日期：2018.9.21

  A Rh(III)-catalyzed C–H activation of boronic acid with aryl azide to obtain unsymmetric carbazoles, 1H-indoles, or indolines has been developed. The reaction constructs dual distinct C–N bonds via sp2/sp3 C–H activation and rhodium nitrene insertion. Synthetically, this approach represents an access to widely used carbazole derivatives. The practical application to CBP and unsymmetric TCTA derivatives

  已开发出一种Rh（III）催化的芳基叠氮化物对硼酸的CHH活化，从而获得不对称的咔唑，1 H吲哚或二氢吲哚。该反应通过sp 2 / sp 3 C-H活化和铑氮烯插入构建了两个不同的C–N键。综合而言，这种方法代表了广泛使用咔唑衍生物的途径。还已经对CBP和不对称TCTA衍生物进行了实际应用。力学实验和DFT计算表明，五元rhodocycle物种是关键的中间体。