N1-(1,2-Dimethylpropyl)-N2-ethyl-1,2-ethanediamine | 1211479-22-9

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: N1-(1,2-Dimethylpropyl)-N2-ethyl-1,2-ethanediamine
• 英文别名: N-ethyl-N'-(3-methylbutan-2-yl)ethane-1,2-diamine
• CAS: 1211479-22-9
• 化学式: C₉H₂₂N₂
• 分子量: 158.28
• InChiKey: DFZCYQDNFPWJKX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.5
• 重原子数：
  11
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  24.1
• 氢给体数：
  2
• 氢受体数：
  2

文献信息

• THERAPEUTIC COMPOUNDS AND METHODS TO TREAT INFECTION
  申请人：RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY

  公开号：US20200325124A1

  公开（公告）日：2020-10-15

  Disclosed herein are compounds of formula (I), or a salt thereof and compositions comprising compounds of formula I that exhibit antibacterial activities, when tested alone and/or in combination with a bacterial efflux pump inhibitor. Also disclosed are methods of treating or preventing a bacterial infection in an animal comprising administering to the animal a compound of formula I alone or in combination with the administration of a bacterial efflux pump inhibitor.