(1S,3aS,5aR,6aR,9aS,10aR,12aR)-3a-Hydroxy-1-[(4R,5R)-5-(4-iodo-3-methyl-butyl)-2,2,4-trimethyl-[1,3]dioxolan-4-yl]-8,8,10a,12a-tetramethyl-1,2,3,3a,5a,6,6a,9a,10,10a,10b,11,12,12a-tetradecahydro-7,9-dioxa-dicyclopenta[a,h]phenanthren-5-one | 133181-49-4

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 类固醇和类固醇衍生物
• 英文名称: (1S,3aS,5aR,6aR,9aS,10aR,12aR)-3a-Hydroxy-1-[(4R,5R)-5-(4-iodo-3-methyl-butyl)-2,2,4-trimethyl-[1,3]dioxolan-4-yl]-8,8,10a,12a-tetramethyl-1,2,3,3a,5a,6,6a,9a,10,10a,10b,11,12,12a-tetradecahydro-7,9-dioxa-dicyclopenta[a,h]phenanthren-5-one
• CAS: 133181-49-4
• 化学式: C₃₃H₅₁IO₆
• 分子量: 670.669
• InChiKey: RJQNSMALMQDZST-XGSOFMNYSA-N

反应信息

• 作为反应物：
  描述：

  (1S,3aS,5aR,6aR,9aS,10aR,12aR)-3a-Hydroxy-1-[(4R,5R)-5-(4-iodo-3-methyl-butyl)-2,2,4-trimethyl-[1,3]dioxolan-4-yl]-8,8,10a,12a-tetramethyl-1,2,3,3a,5a,6,6a,9a,10,10a,10b,11,12,12a-tetradecahydro-7,9-dioxa-dicyclopenta[a,h]phenanthren-5-one 在 高氯酸 作用下， 以 甲醇 为溶剂， 以70%的产率得到26-iodoponasterone A
  参考文献：
  名称：

  Synthesis of 26-iodoponasterone, a new and very active ecdysteroid

  摘要：

  26-Iodoponasterone A, prepared from inokosterone in four steps, is 160 times as the parent compounds in an ecdysone assay on Drosophila Kc cells, and is one of the most active ecdysones known; the 125I is being used for the detection of ecdysone receptors.

  DOI：

  10.1039/c39910000051
• 作为产物：
  描述：

  在 四丁基碘化铵 作用下， 以 甲苯 为溶剂， 反应 19.0h， 以6 mg的产率得到(1S,3aS,5aR,6aR,9aS,10aR,12aR)-3a-Hydroxy-1-[(4R,5R)-5-(4-iodo-3-methyl-butyl)-2,2,4-trimethyl-[1,3]dioxolan-4-yl]-8,8,10a,12a-tetramethyl-1,2,3,3a,5a,6,6a,9a,10,10a,10b,11,12,12a-tetradecahydro-7,9-dioxa-dicyclopenta[a,h]phenanthren-5-one
  参考文献：
  名称：

  Synthesis of 26-iodoponasterone, a new and very active ecdysteroid

  摘要：

  26-Iodoponasterone A, prepared from inokosterone in four steps, is 160 times as the parent compounds in an ecdysone assay on Drosophila Kc cells, and is one of the most active ecdysones known; the 125I is being used for the detection of ecdysone receptors.

  DOI：

  10.1039/c39910000051