(¹⁵N)Thioacetamid | 13385-98-3

• 分子结构分类: 有机化合物 - 有机硫化合物 - 硫代酰胺
• 英文名称: (¹⁵N)Thioacetamid
• 英文别名: ethan(15N)thioamide
• CAS: 13385-98-3
• 化学式: C₂H₅NS
• 分子量: 76.1277
• InChiKey: YUKQRDCYNOVPGJ-LBPDFUHNSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.29
• 重原子数：
  4.0
• 可旋转键数：
  0.0
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  26.02
• 氢给体数：
  1.0
• 氢受体数：
  1.0

反应信息

• 作为产物：
  描述：

  乙酰腈-15N 在 硫化氢 作用下， 以 二乙胺 为溶剂， 反应 3.0h， 以268 mg的产率得到(¹⁵N)Thioacetamid
  参考文献：
  名称：

  A15N nuclear magnetic resonance study of the base-catalyzed NH2 exchange reactions of acetamide and thioacetamide

  摘要：

  AbstractThe base‐catalyzed NH2 exchange reactions of acetamide and thioacetamide were studied by 15N nuclear magnetic resonance spectroscopy by the use of line‐shape analysis. The 15N NMR spectra of these primary amides at intermediate exchange rates were broad doublets, which indicated that the two amide protons were exchanging at different rates. The line‐shape analysis indicated that the ratio of exchange rates was 6±1 for acetamide and 3±1 for thioacetamide.

  DOI：

  10.1002/mrc.1270180302

文献信息

• ANTHONI, U.;NIELSEN, P. H., J. LABELLED COMPOUNDS AND RADIOPHARM., 1984, 21, N 4, 375-380
  作者：ANTHONI, U.、NIELSEN, P. H.

  DOI：——

  日期：——