2-(3-chIorobenzo[b]thiophene-2-carboxamido)-5-(4-chlorophenylcarbamoyl) benzoic acid | 1374775-72-0

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并噻吩类
• 英文名称: 2-(3-chIorobenzo[b]thiophene-2-carboxamido)-5-(4-chlorophenylcarbamoyl) benzoic acid
• 英文别名: 2-[(3-Chloro-1-benzothiophene-2-carbonyl)amino]-5-[(4-chlorophenyl)carbamoyl]benzoic acid
• CAS: 1374775-72-0
• 化学式: C₂₃H₁₄Cl₂N₂O₄S
• 分子量: 485.347
• InChiKey: IEAOLAPFRRFFDD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.3
• 重原子数：
  32
• 可旋转键数：
  5
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  124
• 氢给体数：
  3
• 氢受体数：
  5

文献信息

• BIOMARKERS FOR THE DIAGNOSIS OF INTERSTITIAL CYSTITIS
  申请人：WILLIAM BEAUMONT HOSPITAL

  公开号：US20160274126A1

  公开（公告）日：2016-09-22

  Disclosed are methods for the detection or diagnosis of a patient having symptoms of interstitial cystitis or overactive bladder. Also disclosed are HCN2 modulators and methods for the treatment of interstitial cystitis or overactive bladder.
• [EN] BIOMARKERS FOR THE DIAGNOSIS OF INTERSTITIAL CYSTITIS<br/>[FR] BIOMARQUEURS POUR LE DIAGNOSTIC DE LA CYSTITE INTERSTITIELLE
  申请人：BEAUMONT HOSPITAL WILLIAM

  公开号：WO2014078232A1

  公开（公告）日：2014-05-22

  Disclosed are methods for the detection or diagnosis of a patient having symptoms of interstitial cystitis or overactive bladder. Also disclosed are HCN2 modulators and methods for the treatment of interstitial cystitis or overactive bladder.