6.7-Dimethyl-1-<3.4-dimethyl-benzyl>-3.4-dihydro-isochinolin | 96071-15-7

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 异喹啉及其衍生物
• 英文名称: 6.7-Dimethyl-1-<3.4-dimethyl-benzyl>-3.4-dihydro-isochinolin
• 英文别名: 1-(3,4-dimethyl-benzyl)-6,7-dimethyl-3,4-dihydro-isoquinoline；1-[(3,4-Dimethylphenyl)methyl]-6,7-dimethyl-3,4-dihydroisoquinoline
• CAS: 96071-15-7
• 化学式: C₂₀H₂₃N
• 分子量: 277.409
• InChiKey: SKHSWUMJKLNGOC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.7
• 重原子数：
  21
• 可旋转键数：
  2
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.35
• 拓扑面积：
  12.4
• 氢给体数：
  0
• 氢受体数：
  1

文献信息

• TETRAHYDROPROTOBERBINE COMPOUNDS AND USES THEREOF IN THE TREATMENT OF NEUROLOGICAL, PSYCHIATRIC AND NEURODEGENERATIVE DISEASES
  申请人：MILLER James Jackson

  公开号：US20150306092A1

  公开（公告）日：2015-10-29

  Tetrahydroprotoberbine (THPB) compounds and their use in the treatment of neurological, psychiatric and neurodegenerative diseases is provided. The compounds include d-govadine, l-govadine and racemic govadine, as well as d-THPBs of general formula (I). Enantioselective processes for preparing compounds of formula (I), and d- and l-govadine are also provided.(I)
• US9526721B2
  申请人：——

  公开号：US9526721B2

  公开（公告）日：2016-12-27