Sodium;4-hydroxy-3-nitrobenzenesulfonic acid | 6313-34-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 酚类
• 英文名称: Sodium;4-hydroxy-3-nitrobenzenesulfonic acid
• CAS: 6313-34-4
• 化学式: C6H5NNaO6S+
• 分子量: 242.16
• InChiKey: CKYLHMGDNIAAPE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -2.45
• 重原子数：
  15
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  129
• 氢给体数：
  2
• 氢受体数：
  6

文献信息

• HIV protease inhibiting compounds
  申请人：Flentge Charles A.

  公开号：US20110003827A1

  公开（公告）日：2011-01-06

  A compound of the formula is disclosed as an HIV protease inhibitor. Methods and compositions for inhibiting an HIV infection are also disclosed.

  公开了一种具有以下公式的化合物，作为HIV蛋白酶抑制剂。还公开了抑制HIV感染的方法和组合物。
• Bisaryl-sulfonamides
  申请人：Bergeron Philippe

  公开号：US20060084802A1

  公开（公告）日：2006-04-20

  Compounds, compositions and methods are provided that are useful in the treatment or prevention of a condition or disorder mediated by PPARγ or PPARδ. In particular, the compounds of the invention modulate the function of PPARγ or PPARδ. The subject methods are particularly useful in the treatment and/or prevention of diabetes, obesity, hypercholesterolemia, rheumatoid arthritis and atherosclerosis.

  提供了在治疗或预防由PPARγ或PPARδ介导的疾病或紊乱方面有用的化合物、组合物和方法。具体来说，本发明的化合物调节PPARγ或PPARδ的功能。该方法特别适用于治疗和/或预防糖尿病、肥胖症、高胆固醇血症、类风湿性关节炎和动脉粥样硬化。
• HIV PROTEASE INHIBITING COMPOUNDS
  申请人：Flentge Charles A.

  公开号：US20130023463A1

  公开（公告）日：2013-01-24

  A compound of the formula is disclosed as an HIV protease inhibitor. Methods and compositions for inhibiting an HIV infection are also disclosed.

  该化合物的公式被披露为HIV蛋白酶抑制剂。还披露了抑制HIV感染的方法和组合物。
• Peptide antibodies and their use in detecting oncogene products
  申请人：CETUS CORPORATION

  公开号：EP0175360A2

  公开（公告）日：1986-03-26

  Antibodies exhibit specificity toward single amino acid differences between proteins. These antibodies may be produced by synthesizing a peptide of the appropriate amino acid sequence contained in the protein, immunizing a host with the peptide, and extracting sera from the host to obtain the antibodies. The antibodies and the desired protein are then immunoprecipiated under conditions of partial denaturation to expose the epitope of the protein. The antibodies may be used for diagnostic or therapeutic purposes.

  抗体对蛋白质之间的单个氨基酸差异具有特异性。这些抗体可以通过合成蛋白质中含有的适当氨基酸序列的多肽，用多肽免疫宿主，并从宿主中提取血清以获得抗体来产生。然后在部分变性的条件下对抗体和所需蛋白质进行免疫沉淀，以暴露蛋白质的表位。抗体可用于诊断或治疗目的。
• Hiv protease inhibiting sulfonamides
  申请人：Abbott Laboratories

  公开号：EP2216334A1

  公开（公告）日：2010-08-11

  A compound of the formula is disclosed as an I-IIV protease inhibitor. Methods and compositions for inhibiting an HIV infection are also disclosed.

  式中的化合物 公开了一种 I-IIV 蛋白酶抑制剂。还公开了抑制艾滋病毒感染的方法和组合物。