Pentacosylamin | 14130-09-7

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: Pentacosylamin
• 英文别名: Pentacosan-1-amine
• CAS: 14130-09-7
• 化学式: C₂₅H₅₃N
• 分子量: 367.703
• InChiKey: ILNYGCPXYZULFZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  12.3
• 重原子数：
  26
• 可旋转键数：
  23
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  26
• 氢给体数：
  1
• 氢受体数：
  1

文献信息

• ABUSE DETERRENT AND ANTI-DOSE DUMPING PHARMACEUTICAL SALTS USEFUL FOR THE TREATMENT OF ATTENTION DEFICIT/HYPERACTIVITY DISORDER
  申请人：King Clifford Riley

  公开号：US20120028960A1

  公开（公告）日：2012-02-02

  A pharmaceutical composition comprising a drug substance consisting essentially of a pharmaceutically acceptable organic acid addition salt of an amine containing pharmaceutically active compound wherein the amine containing pharmaceutical active compound is selected from the group consisting of racemic or single isomer ritalinic acid or phenethylamine derivatives and the drug substance has a physical form selected from amorphous and polymorphic.

  一种药物组合物，包括基本上由含有药用活性化合物的胺的药用可接受的有机酸加合盐组成的药物物质，其中含有药用活性化合物的胺被选择自光学异构体或单异构体利他林酸或苯乙胺衍生物的群体，并且该药物物质具有从无定形到多型的物理形式。
• Heteroatom bridged metallocene compounds for olefin polymerization
  申请人：Voskoboynikov Z. Alexander

  公开号：US20070135597A1

  公开（公告）日：2007-06-14

  This invention relates to a transition metal compound represented by the formula: wherein M is a group 3, 4, 5 or 6 transition metal atom, or a lanthanide metal atom, or actinide metal atom; E is: 1) a substituted or unsubstituted indenyl ligand that is bonded to Y through the four, five, six or seven position of the indenyl ring, or 2) a substituted or unsubstituted heteroindenyl ligand that is bonded to Y through the four, five or six position of the heteroindenyl ring, provided that the bonding position is not the same as the position of the ring heteroatom, or 3) a substituted or unsubstituted fluorenyl ligand that is bonded to Y through the one, two, three, four, five, six, seven or eight position of the fluorenyl ring, or 4) a substituted or unsubstituted heterofluorenyl ligand that is bonded to Y through the one, two, three, four, five or six position of the heteroindenyl ring, provided that the bonding position is not the same as the position of the ring heteroatom; A is a substituted or unsubstituted cyclopentadienyl ligand, a substituted or unsubstituted heterocyclopentadienyl ligand, a substituted or unsubstituted indenyl ligand, a substituted or unsubstituted heteroindenyl ligand, a substituted or unsubstituted fluorenyl ligand, a substituted or unsubstituted heterofluorenyl ligand, or other mono-anionic ligand; Y is a Group 15 or 16 bridging heteroatom substituent that is bonded via the heteroatom to E and A; and X are, independently, univalent anionic ligands, or both X are joined and bound to the metal atom to form a metallocycle ring, or both X join to form a chelating ligand, a diene ligand, or an alkylidene ligand. This invention further relates to catalyst systems comprising the above transiotioon metal compounds, activators and optional supports and their use to polymerize or oligomerize olefins.

  本发明涉及一种过渡金属化合物，其表示为以下公式：其中M是3、4、5或6族过渡金属原子，或镧系金属原子，或锕系金属原子；E是：1）与Y通过茚环的四、五、六或七位置结合的取代或未取代的茚基配体，或2）与Y通过杂环茚环的四、五或六位置结合的取代或未取代的杂环茚基配体，前提是结合位置与环杂原子的位置不同，或3）与Y通过芴环的一、二、三、四、五、六、七或八位置结合的取代或未取代的芴基配体，或4）与Y通过杂芴环的一、二、三、四、五或六位置结合的取代或未取代的杂芴基配体，前提是结合位置与环杂原子的位置不同；A是取代或未取代的环戊二烯基配体，取代或未取代的杂环戊二烯基配体，取代或未取代的茚基配体，取代或未取代的杂环茚基配体，取代或未取代的芴基配体，取代或未取代的杂芴基配体，或其他单阴离子配体；Y是通过杂原子与E和A结合的15族或16族桥接杂原子取代基；X是独立的一价阴离子配体，或两个X结合并与金属原子结合形成金属环，或两个X结合形成螯合配体、二烯基配体或烷基亚基配体。本发明还涉及包含上述过渡金属化合物、活化剂和可选支撑物的催化剂系统及其用于聚合或寡聚烯烃的用途。
• Functional associative coatings for nanoparticles
  申请人：Hainfeld James F.

  公开号：US20080089836A1

  公开（公告）日：2008-04-17

  Described herein are nanoparticles that are coated with a bilayer of molecules formed from surface binding molecules and amphiphatic molecules. The bilayer coating self assembles on the nanoparticles from readily available materials/molecules. The modular design of the bilayer coated nanoparticles provides a means for readily and efficiently optimizing the properties of the bilayer coated nanoparticle compositions. Also described herein are uses of such nanoparticles in medicine, laboratory techniques, industrial and commerical applications.

  本文描述了一种纳米颗粒，其表面涂覆有由表面结合分子和两亲分子形成的双层分子层。该双层涂层可以自组装在纳米颗粒上，使用易得的材料/分子。双层涂层纳米颗粒的模块化设计提供了一种方便和高效地优化其性质的方法。此外，本文还描述了这种纳米颗粒在医学、实验室技术、工业和商业应用中的用途。
• Complexed surfactant system
  申请人：Ko Ki-Hwan

  公开号：US20050164903A1

  公开（公告）日：2005-07-28

  The present invention relates to a mixed surfactant system, and particularly to a mixed surfactant system which comprises an anionic surfactant and a compound comprising at least one kind of non-ionic group or cationic group, and which thus increases cleaning power of the anionic surfactant, increases stability to hard water, lowers surface tension and cmc, and can control initial foamability and foam stability by the mixing ratio of the non-ionic surfactant and the cationic surfactant that can be added together, and that is therefore very useful for a detergent of solid, liquid, gel, or paste types.

  本发明涉及一种混合表面活性剂系统，特别是一种包含阴离子表面活性剂和至少一种非离子基团或阳离子基团的化合物的混合表面活性剂系统，从而增强阴离子表面活性剂的清洁能力，增加对硬水的稳定性，降低表面张力和cmc，并且可以通过非离子表面活性剂和阳离子表面活性剂的混合比例来控制初始泡沫性和泡沫稳定性，因此非常适用于固体、液体、凝胶或糊状洗涤剂。
• Phenylacetonitrile derivatives and hair tonics and external preparations for skin containing the derivatives
  申请人：Hanyu Naoto

  公开号：US20050176822A1

  公开（公告）日：2005-08-11

  A hair growth promoting composition comprising, as an effective ingredient, a phenylacetonitrile derivative or a pharmacologically acceptable salt thereof expressed by the following Formula (I): wherein each of R 1 and R 2 is hydrogen atom, a C 1-10 alkyl group, a C 2-10 alkenyl group or C 2-10 acyl group, or NR 1 R 2 may be a heterocycle having 3-7 members; R 3 is a C 1-5 alkyl group; and each of R 4 , R 5 and R 6 is hydrogen atom or a C 1-4 alkoxy group. The present invention provides a hair growth promoting composition having excellent effects on promoting hair regrowth, preventing or inhibiting hair loss, and the like in human by compounding above-specified phenylacetonitrile derivative as a effective ingredient thereto.

  一种促进头发生长的组合物，包括以下式子（I）表示的苯乙腈衍生物或其药学上可接受的盐作为有效成分：其中R1和R2中的每一个均为氢原子，C1-10烷基，C2-10烯基或C2-10酰基，或者NR1R2可以是具有3-7个成员的杂环；R3为C1-5烷基；R4、R5和R6中的每一个均为氢原子或C1-4烷氧基。本发明提供了一种促进头发再生、预防或抑制脱发等在人体上具有优异效果的头发生长促进组合物，其中上述苯乙腈衍生物作为有效成分混合在其中。