2-methyl-thioxantheno[2,1,9-def]isoquinoline-1,3-dione | 14930-90-6

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 异喹啉及其衍生物
• 英文名称: 2-methyl-thioxantheno[2,1,9-def]isoquinoline-1,3-dione
• 英文别名: 14-Methyl-8-thia-14-azapentacyclo[10.6.2.02,7.09,19.016,20]icosa-1(19),2,4,6,9,11,16(20),17-octaene-13,15-dione
• CAS: 14930-90-6
• 化学式: C₁₉H₁₁NO₂S
• 分子量: 317.368
• InChiKey: KYMALTOFBKNJPQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.9
• 重原子数：
  23
• 可旋转键数：
  0
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.05
• 拓扑面积：
  62.7
• 氢给体数：
  0
• 氢受体数：
  3

文献信息

• POLY(ETHYLENE GLYCOL) DERIVATIVES FOR CLICK CHEMISTRY
  申请人：Sill Kevin

  公开号：US20130178600A1

  公开（公告）日：2013-07-11

  The present invention provides bifunctional polymers, methods of preparing the same, and intermediates thereto. These compounds are useful in a variety of applications including the PEGylation of biologically active molecules. The invention also provides methods of using said compounds and compositions thereof.

  本发明提供了双功能聚合物，其制备方法及其中间体。这些化合物在各种应用中都很有用，包括对生物活性分子进行聚乙二醇化。本发明还提供了使用上述化合物及其组合物的方法。
• HYBRID BLOCK COPOLYMER MICELLES WITH MIXED STEREOCHEMISTRY FOR ENCAPSULATION OF HYDROPHOBIC AGENTS
  申请人：Intezyne Technologies, Inc.

  公开号：US20150232616A1

  公开（公告）日：2015-08-20

  The present invention relates to the field of polymer chemistry and more particularly to multiblock copolymers and micelles comprising the same.

  本发明涉及聚合物化学领域，更具体地涉及多嵌段共聚物及包含其的胶束。
• Coloring composition of keratinous fibers comprising at least one polysiloxane/polyurea block copolymer
  申请人：Brun Gaelle

  公开号：US20080127429A1

  公开（公告）日：2008-06-05

  Disclosed herein is a composition comprising at least one nonionic polysiloxane/polyurea block copolymer, at least one colored or coloring entity, and at least one volatile nonsilicone organic solvent. Such a composition may make it possible to obtain a coloring which is resistant to external agents.
• Composition comprising a compound X and A compound Y, at least one of which is a silicone, and a hydrophobic direct dye
  申请人：Brun Gaelle

  公开号：US20080184496A1

  公开（公告）日：2008-08-07

  The present disclosure relates to a composition for coloring keratin fibers comprising a cosmetically acceptable medium, at least one compound X at least one compound Y, wherein at least one of the compounds X and Y is a silicone compound, wherein when X and Y are placed in contact with each other they react together via a hydrosilylation reaction, a condensation reaction, or a crosslinking reaction in the presence of at least one peroxide, at least one hydrophobic direct dye having a log P greater than 2, and optionally at least one organic solvent. The composition of the disclosure makes it possible to obtain varied hues and intense colors on the keratin fibers. Moreover, the coloration obtained is very resistant to external agents, for example, to repeated washing.
• SULFUR-CONTAINING NAPHTHALIMIDE DERIVATIVES
  申请人：Qian Xuhong

  公开号：US20080234287A1

  公开（公告）日：2008-09-25

  The invention discloses novel sulfur-containing naphthalimide derivatives, and the preparation and uses thereof. The conjugated plane of naphthalimide derivatives of the invention is enlarged by incorporating 5- or 6-membered heteroaromatic ring and/or introducing S heteroatom, thus increasing the anti-tumor activity of naphthalimide. The compounds of the invention displays significant inhibiting activities to the proliferation of various tumor cells such as human lung cancer, gastric cancer, liver cancer, leucocythemia and the like. The inhibition of cell proliferation is dose-dependent.