| 173557-39-6

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 类固醇和类固醇衍生物
• CAS: 173557-39-6
• 化学式: C₂₄H₃₄O₂Si
• 分子量: 382.618
• InChiKey: JYISQVRXWUVHHQ-FIXSFTCYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.41
• 重原子数：
  27.0
• 可旋转键数：
  2.0
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.58
• 拓扑面积：
  29.46
• 氢给体数：
  1.0
• 氢受体数：
  2.0

反应信息

• 作为反应物：
  描述：

  在 四丁基氟化铵 、 三苯基膦 、 偶氮二甲酸二乙酯 作用下， 以 甲苯 为溶剂， 反应 1.5h， 生成
  参考文献：
  名称：

  Alcohol inversion of 17β-steroids

  摘要：

  Inversion of 17 beta-steroids has been accomplished using a modified Mitsunobu protocol in which 4-nitrobenzoic acid is employed as the acidic component. Excellent yields of inverted product were obtained for a number of representative steroid families including estrogens, equilenins, and androgens. Application of this methodology to the synthesis of 17 alpha-dihydroequilenin is described.

  DOI：

  10.1016/0960-894x(95)00559-c
• 作为产物：
  描述：

  在 lithium aluminium tetrahydride 作用下， 生成
  参考文献：
  名称：

  Alcohol inversion of 17β-steroids

  摘要：

  Inversion of 17 beta-steroids has been accomplished using a modified Mitsunobu protocol in which 4-nitrobenzoic acid is employed as the acidic component. Excellent yields of inverted product were obtained for a number of representative steroid families including estrogens, equilenins, and androgens. Application of this methodology to the synthesis of 17 alpha-dihydroequilenin is described.

  DOI：

  10.1016/0960-894x(95)00559-c