(2,4-二甲基-1-氧基吡啶-3-基)[4-甲基-4-(苯基吡啶-3-基氨基)-[1,4]bi哌啶基-1-基]-甲酮 | 470689-87-3

• 分子结构分类: 有机化合物 - 有机氮化合物
• 中文名称: (2,4-二甲基-1-氧基吡啶-3-基)[4-甲基-4-(苯基吡啶-3-基氨基)-[1,4]bi哌啶基-1-基]-甲酮
• 英文名称: Unii-LV99ztj3GS
• 英文别名: (2,4-dimethyl-1-oxidopyridin-1-ium-3-yl)-[4-methyl-4-[4-(N-pyridin-3-ylanilino)piperidin-1-yl]piperidin-1-yl]methanone
• CAS: 470689-87-3
• 化学式: C30H37N5O2
• 分子量: 499.6
• InChiKey: DDVVRHNNOPQPGB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.7
• 重原子数：
  37
• 可旋转键数：
  5
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.43
• 拓扑面积：
  65.1
• 氢给体数：
  0
• 氢受体数：
  5

文献信息

• BIOMARKERS FOR GRAFT REJECTION
  申请人：Novartis AG

  公开号：EP1694860A2

  公开（公告）日：2006-08-30
• Biomarkers for graft rejection
  申请人：Bigaud Marc

  公开号：US20070111210A1

  公开（公告）日：2007-05-17

  Methods are disclosed for diagnosing rejection in a transplanted subject, monitoring rejection in a transplanted subject at risk thereof, preventing, inhibiting, reducing or treating rejection in a transplanted subject, or identifying agents for use in the prevention, inhibition, reduction or treatment of rejection, based on genes which are differentially expressed in transplanted subjects.
• Biomarkers for Graft Rejection
  申请人：Bigaud Marc

  公开号：US20120039868A1

  公开（公告）日：2012-02-16

  Methods are disclosed for diagnosing rejection in a transplanted subject, monitoring rejection in a transplanted subject at risk thereof, preventing, inhibiting, reducing or treating rejection in a transplanted subject, or identifying agents for use in the prevention, inhibition, reduction or treatment of rejection, based on genes which are differentially expressed in transplanted subjects.
• [EN] BIOMARKERS FOR GRAFT REJECTION<br/>[FR] MARQUEURS BIOLOGIQUES POUR LE REJET DE GREFFE
  申请人：NOVARTIS AG

  公开号：WO2005054503A2

  公开（公告）日：2005-06-16

  Methods are disclosed for diagnosing rejection in a transplanted subject, monitoring rejection in a transplanted subject at risk thereof, preventing, inhibiting, reducing or treating rejection in a transplanted subject, or identifying agents for use in the prevention, inhibition, reduction or treatment of rejection, based on genes which are differentially expressed in transplanted subjects.