N-{8-[3,5-bis(trifluoromethyl)phenyl]naphthalen-1-yl}pyridine-2-carboxamide | 1609158-96-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: N-{8-[3,5-bis(trifluoromethyl)phenyl]naphthalen-1-yl}pyridine-2-carboxamide
• CAS: 1609158-96-4
• 化学式: C₂₄H₁₄F₆N₂O
• 分子量: 460.378
• InChiKey: YODOHYNYRAZNQR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.19
• 重原子数：
  33.0
• 可旋转键数：
  3.0
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.08
• 拓扑面积：
  41.99
• 氢给体数：
  1.0
• 氢受体数：
  2.0

反应信息

• 作为反应物：
  描述：

  N-{8-[3,5-bis(trifluoromethyl)phenyl]naphthalen-1-yl}pyridine-2-carboxamide 在 sodium tetrahydroborate 、 甲酸 、 水 、 sodium hexamethyldisilazane 、 potassium hydroxide 作用下， 以 四氢呋喃 、 甲醇 、 乙醇 、 二氯甲烷 为溶剂， 反应 51.0h， 生成
  参考文献：
  名称：

  Secondary Alkene Insertion and Precision Chain-Walking: A New Route to Semicrystalline “Polyethylene” from α-Olefins by Combining Two Rare Catalytic Events

  摘要：

  While traditional polymerization of linear alpha-olefins (LAOs) typically provides amorphous, low T-g polymers, chain-straightening polymerization represents a route to semicrystalline materials. A series of alpha-diimine nickel catalysts were tested for the polymerization of various LAOs. Although known systems yielded amorphous or low-melting polymers, the "sandwich" alpha-diimines 3-6 yielded semicrystalline "polyethylene" comprised primarily of unbranched repeat units via a combination of uncommon regioselective 2,1-insertion and precision chain-walking events.

  DOI：

  10.1021/ja502130w
• 作为产物：
  描述：

  N-(naphthalen-1-yl)picolinamide 、 3,5-双(三氟甲基)碘苯 在 silver(I) acetate 、 palladium diacetate 作用下， 反应 13.0h， 以60%的产率得到N-{8-[3,5-bis(trifluoromethyl)phenyl]naphthalen-1-yl}pyridine-2-carboxamide
  参考文献：
  名称：

  Secondary Alkene Insertion and Precision Chain-Walking: A New Route to Semicrystalline “Polyethylene” from α-Olefins by Combining Two Rare Catalytic Events

  摘要：

  While traditional polymerization of linear alpha-olefins (LAOs) typically provides amorphous, low T-g polymers, chain-straightening polymerization represents a route to semicrystalline materials. A series of alpha-diimine nickel catalysts were tested for the polymerization of various LAOs. Although known systems yielded amorphous or low-melting polymers, the "sandwich" alpha-diimines 3-6 yielded semicrystalline "polyethylene" comprised primarily of unbranched repeat units via a combination of uncommon regioselective 2,1-insertion and precision chain-walking events.

  DOI：

  10.1021/ja502130w