3,3'-Diethyl-thiatricarbocyanin | 252047-32-8

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并噻唑类
• 英文名称: 3,3'-Diethyl-thiatricarbocyanin
• 英文别名: (2Z)-3-ethyl-2-[(2E)-7-(3-ethyl-1,3-benzothiazol-3-ium-2-yl)hepta-2,4,6-trienylidene]-1,3-benzothiazole
• CAS: 252047-32-8
• 化学式: C₂₅H₂₅N₂S₂
• mdl: MFCD00625776
• 分子量: 417.619
• InChiKey: UMTQICYFVVKJFV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.6
• 重原子数：
  29
• 可旋转键数：
  6
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.16
• 拓扑面积：
  60.7
• 氢给体数：
  0
• 氢受体数：
  3

文献信息

• Perfluorinated amide salts and their uses as ionic conducting materials
  申请人：——

  公开号：US20020009650A1

  公开（公告）日：2002-01-24

  The invention concerns ionic compounds in which the anionic load has been delocalized. A compound disclosed by the invention is comprised of an amide or one of its salts, including an anionic portion combined with at least one cationic portion M +m in sufficient numbers to ensure overall electronic neutrality; the compound is further comprised of M as a hydroxonium, a nitrosonium NO + , an ammonium —NH 4 +, a metallic cation with the valence m, an organic cation with the valence m, or an organometallic cation with the valence m. The anionic portion matches the formula R F —SO x —N − Z, wherein R F is a perfluorinated group, x is 1 or 2, and Z is an electroattractive substituent. The compounds can be used notably for ionic conducting materials, electronic conducting materials, colorants, and the catalysis of various chemical reactions.

  该发明涉及离子化合物，其中阴离子载荷已被解离。该发明揭示的一种化合物由酰胺或其盐之一组成，包括与至少一个阳离子部分M+min结合以确保整体电子中性；该化合物进一步由M作为氢氧离子、亚硝基 NO+、铵离子—NH4+、具有价态m的金属阳离子、具有价态m的有机阳离子，或具有价态m的有机金属阳离子组成。阴离子部分符合公式RF—SOx—N−Z，其中RF是全氟化基团，x为1或2，Z是一个电子吸引取代基。这些化合物可以用于离子导电材料、电子导电材料、着色剂以及各种化学反应的催化。
• MOLECULAR PROBES FOR IMAGING MYELIN
  申请人：Wang Yanming

  公开号：US20130209357A1

  公开（公告）日：2013-08-15

  A molecular probe for use in the detection of myelin in a subject includes a compound having the general formula selected from the group consisting of: formula (I), and pharmaceutically acceptable salts thereof.

  用于检测受试者中髓鞘的分子探针包括具有以下通式的化合物，以及其药用可接受的盐。
• [EN] DEVELOPMENT OF PHOTOSTABLE NEAR-IR CYANINE DYES FOR IN VIVO IMAGING<br/>[FR] RÉVÉLATION DE COLORANTS CYANINE PHOTOSTABLES PROCHES DE L'IR POUR L'IMAGERIE IN VIVO
  申请人：UNIV SINGAPORE

  公开号：WO2011119114A1

  公开（公告）日：2011-09-29

  A compound of structural formula (I). The values and alternative values are as defined herein. The invention also includes biosensors comprising nanoparticles functionalized with a compound of structural formula (I). Also described is a method for labeling a biomolecule using a compound of structural formula (I) and a method of detecting a target biomolecule using a compound of structural formula (I) or a biosensor of the invention.

  结构式（I）的化合物。所述数值和备选数值如本文所定义。该发明还包括具有功能化为结构式（I）的纳米颗粒的生物传感器。还描述了一种使用结构式（I）的化合物标记生物分子的方法，以及使用结构式（I）的化合物或本发明的生物传感器检测目标生物分子的方法。
• [EN] FLUORESCENT SOLID LIPID NANOPARTICLES COMPOSITION AND PREPARATION THEREOF<br/>[FR] COMPOSITION DE NANOPARTICULES LIPIDES SOLIDES FLUORESCENTES ET SA PRÉPARATION
  申请人：BRACCO IMAGING SPA

  公开号：WO2014191467A1

  公开（公告）日：2014-12-04

  The present invention discloses a solid lipid nanoparticle (SLN) comprising: a) a solid lipid core comprising at least a glyceride and/or at least a fatty acid; b) a mixture of amphiphilic components forming a shell around said core a); c) an alkaline-earth complex with a compound of formula I and/or II: d) at least a fluorescent dye selected from: a cyanine fluorescent dye and /or a polyetherocyclic compound selected from: coumarin, pyrano, quinoline, pyranoquinoline, indole and pyranoindole derivates in acid form or a pharmaceutically acceptable salt thereof. These nanoparticles allow a prolonged blood circulation half-life, show enhanced photostability and improved fluorescence signal. The dye is preserved from degradation and improves the fluorescent quantum yield.

  本发明公开了一种固体脂质纳米粒子（SLN），包括：a）至少包括一种甘油酯和/或至少一种脂肪酸的固体脂质核心；b）形成围绕所述核心a）的壳层的两性分子成分混合物；c）与式I和/或II的化合物形成的碱土金属络合物；d）至少选择自：青菁荧光染料和/或选择自：香豆素、吡喍、喹啉、吡喍喹啉、吲哚和吡喍吲哚衍生物的多醚环化合物的荧光染料；以及其在酸形式或其药学上可接受的盐中。这些纳米粒子允许延长血液循环半衰期，显示增强的光稳定性和改善的荧光信号。染料免受降解并提高荧光量子产率。
• Malononitrile-derivative anion salts, and their uses as ionic conducting materials
  申请人：——

  公开号：US20030066988A1

  公开（公告）日：2003-04-10

  The invention is related to ionic compounds, derivatives of malononitrile, in which the anionic load has been displaced. An ionic compound disclosed by the invention includes an anionic portion combined with at least one cationic portion M +m in sufficient number to ensure overall electronic neutrality; the compound is further comprised of M as a hydroxonium, a nitrosonium NO + , an ammonium —NH 4 +, a metallic cation with the valence m, an organic cation with the valence m, or an organometallic cation with the valence m. The anionic portion corresponds to one of the formulas R D —Y—C(C≡N) 2 − or Z-C(C≡N) 2 − in which Z is an electroattractive group, R D is an organic radical, and Y is a carbonyl, a thiocarbonyl, a sulfonyl, a sulfinyl, or a phosphonyl. The compounds can be used notably for ionic conducting materials, electronic conducting materials, colorants, and the catalysis of various chemical reactions.

  这项发明涉及到马隆腈的衍生物，其中阴离子负荷已被移位的离子化合物。本发明揭示的一种离子化合物包括一个阴离子部分与至少一个阳离子部分M+min的组合，以确保整体电子中性；该化合物进一步由M作为氢氧根离子、亚硝酰离子NO+、铵离子—NH4+、带有价态m的金属阳离子、带有价态m的有机阳离子或带有价态m的有机金属阳离子组成。阴离子部分对应于以下公式之一：RD—Y—C(C≡N)2−或Z-C(C≡N)2−，其中Z是一个电子吸引基团，RD是一个有机基团，Y是一个羰基、硫代羰基、磺酰基、亚磺酰基或膦酰基。这些化合物可用于离子导电材料、电子导电材料、染料和各种化学反应的催化剂。