1-amino-3,5-dimethyl-adamantane hydrobromide | 952413-72-8

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: 1-amino-3,5-dimethyl-adamantane hydrobromide
• 英文别名: 3,5-Dimethyl-1-aminoadamantane hydrobromide；3,5-dimethyladamantan-1-amine;hydrobromide
• CAS: 952413-72-8
• 化学式: BrH*C₁₂H₂₁N
• 分子量: 260.217
• InChiKey: YETLGNWTJIRFIL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.27
• 重原子数：
  14
• 可旋转键数：
  0
• 环数：
  4.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  26
• 氢给体数：
  2
• 氢受体数：
  1

文献信息

• MEMANTINE FORMULATIONS
  申请人：DEDHIYA Mahendra G.

  公开号：US20090247644A1

  公开（公告）日：2009-10-01

  The present invention relates to pharmaceutical compositions prepared from equant-shaped crystals of memantine, such as orally dissolving formulations, e.g., tablets (ODTs) and films (ODFs), and to methods of treating conditions, including childhood behavioral disorders (e.g., autism) and Alzheimer's disease by administering the same.
• US4122193A
  申请人：——

  公开号：US4122193A

  公开（公告）日：1978-10-24
• [EN] MEMANTINE FORMULATIONS<br/>[FR] FORMULATIONS DE MÉMANTINE
  申请人：FOREST LAB HOLDINGS LTD

  公开号：WO2009151498A2

  公开（公告）日：2009-12-17

  The present invention relates to pharmaceutical compositions prepared from equant-shaped crystals of memantine, such as orally dissolving formulations, e.g., tablets (ODTs) and films (ODFs), and to methods of treating conditions, including childhood behavioral disorders (e.g., autism) and Alzheimer's disease by administering the same.