2-Pentyl-thiophan | 3050-98-4

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 硫杂环戊烷
• 英文名称: 2-Pentyl-thiophan
• 英文别名: 2-Pentylthiolane
• CAS: 3050-98-4
• 化学式: C₉H₁₈S
• 分子量: 158.308
• InChiKey: QQVRCOSRKOIMKB-UHFFFAOYSA-N

物化性质

• 保留指数：
  1238;1238

计算性质

• 辛醇/水分配系数(LogP)：
  3.8
• 重原子数：
  10
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  25.3
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  alkaline earth salt of/the/ methylsulfuric acid 在 sodium sulfide 、 乙醇 作用下， 生成 2-Pentyl-thiophan
  参考文献：
  名称：

  Obolenzew; Bucharow, 1957, p. 9,14, 17

  摘要：

  DOI：

文献信息

• Stereospecific cyclodehydration of 1,4-sulfanylalcohols to thiolanes: mechanistic insights
  作者：Jean-Jacques Filippi、Elisabet Duñach、Xavier Fernandez、Uwe J. Meierhenrich

  DOI：10.1016/j.tet.2008.07.088

  日期：2008.10

  A series of thiolanes were prepared by cyclodehydration of sulfanylalcohols in the presence of catalytic amounts of p-toluenesulfonic acid or by using K10 clay. The sulfur heterocycles were synthesised in good to excellent yields using either a conventional Dean–Stark method or microwave irradiation under solvent-free conditions. The reaction could be performed regio- and stereoselectively and its

  在催化量的对甲苯磺酸存在下，通过环硫烷硫醇的脱水反应或使用K10粘土制备了一系列硫杂环戊烷。使用常规的迪安-斯达克方法或在无溶剂条件下用微波辐照，可以很好地合成优良的硫杂环化合物。该反应可以区域和立体选择性地进行，并且通过对映体和非对映体富集的底物研究了其机理。相较于以前的研究，我们的结果与分子内的一致ň 2型机构作为一般的途径。
• [EN] INTEGRATED PROCESS FOR PRODUCING CYCLIC ACETALS AND OXYMETHYLENE POLYMERS<br/>[FR] PROCÉDÉ INTÉGRÉ DE PRODUCTION D'ACÉTALS CYCLIQUES ET DE POLYMÈRES D'OXYMÉTHYLÈNE
  申请人：TICONA GMBH

  公开号：WO2013076288A1

  公开（公告）日：2013-05-30

  A process for producing cyclic acetals is described. A formaldehyde source is contacted with an aprotic compound in the presence of a catalyst to produce the cyclic acetals. The aprotic compound can increase conversion rates and/or efficiency. In one embodiment, the formaldehyde source is obtained from methanol. In particular, methanol can be converted into formaldehyde which is then converted into a cyclic acetal. In one embodiment, the cyclic acetal can then be used to produce oxymethylene polymers.

  本文描述了一种制备环状缩醛的过程。在催化剂的存在下，将甲醛源与非质子溶剂化合物接触以产生环状缩醛。非质子溶剂可以提高转化率和/或效率。在一种实施方式中，甲醛源来自甲醇。特别地，甲醇可以转化为甲醛，然后再转化为环状缩醛。在一种实施方式中，环状缩醛可以用于制备氧甲基聚合物。
• [EN] PROCESS FOR PRODUCING A CYCLIC ACETAL IN A HETEROGENEOUS REACTION SYSTEM<br/>[FR] PROCÉDÉ DE PRODUCTION D'UN ACÉTAL CYCLIQUE DANS UN SYSTÈME RÉACTIONNEL HÉTÉROGÈNE
  申请人：TICONA GMBH

  公开号：WO2013076290A1

  公开（公告）日：2013-05-30

  A process for producing a cyclic acetal is disclosed. According to the process, a formaldehyde source is combined with an aprotic compound and contacted with a heterogeneous catalyst which causes the formaldehyde source to convert into a cyclic acetal such as trioxane. The catalyst, for instance, may comprise a solid catalyst such as an ion exchange resin. In one embodiment, the process is used for converting anhydrous formaldehyde gas to trioxane. The anhydrous formaldehyde gas may be produced form an aqueous formaldehyde solution by an extractive distillation.

  本发明揭示了一种生产环状缩醛的工艺。根据该工艺，将甲醛源与无质子溶剂化合物结合，并与使甲醛源转化为环状缩醛的异相催化剂接触。例如，催化剂可以包括固体催化剂，如离子交换树脂。在一种实施例中，该工艺用于将无水甲醛气体转化为三聚氧杂环己烷。无水甲醛气体可以通过萃取蒸馏从水甲醛溶液中产生。
• α‐Functionalisation of Cyclic Sulfides Enabled by Lithiation Trapping
  作者：Nico Seling、Masakazu Atobe、Kevin Kasten、James D. Firth、Peter B. Karadakov、Frederick W. Goldberg、Peter O'Brien

  DOI：10.1002/anie.202314423

  日期：2024.1.8

  Lithiation and trapping at convenient temperatures (0/−10 °C) of five cyclic sulfides such as tetrahydrothiophene, tetrahydrothiopyrans and a thiomorpholine enables straightforward α-functionalisation. Trapping with a wide range of electrophiles generates more than 50 diverse α-substituted saturated sulfur heterocycles that are not easily synthesised by the currently available methods. TMEDA=N,N,N′

  五种环状硫化物（例如四氢噻吩、四氢噻喃和硫代吗啉）在方便的温度（0/−10 °C）下进行锂化和捕获，可实现直接的 α 官能化。用多种亲电子试剂捕获会产生 50 多种不同的 α-取代饱和硫杂环，这些杂环不易通过当前可用的方法合成。 TMEDA= N,N,N′,N′-四甲基乙二胺
• Process for producing a cyclic acetal in a heterogeneous reaction system
  申请人：Celanese Sales Germany GmbH

  公开号：US10829467B2

  公开（公告）日：2020-11-10

  A process for producing a cyclic acetal is disclosed. According to the process, a formaldehyde source is combined with an aprotic compound and contacted with a heterogeneous catalyst which causes the formaldehyde source to convert into a cyclic acetal such as trioxane. The catalyst, for instance, may comprise a solid catalyst such as an ion exchange resin. In one embodiment, the process is used for converting anhydrous formaldehyde gas to trioxane. The anhydrous formaldehyde gas may be produced form an aqueous formaldehyde solution by an extractive distillation. The aprotic compound and the formaldehyde solution may be extracted from the reaction product and recycled into the process.

  本发明公开了一种生产环缩醛的工艺。根据该工艺，甲醛源与惰性化合物结合，并与异相催化剂接触，使甲醛源转化为环缩醛（如三氧六环）。例如，催化剂可包括固体催化剂，如离子交换树脂。在一个实施方案中，该工艺用于将无水甲醛气体转化为三氧环己烷。无水甲醛气体可通过萃取蒸馏生成甲醛水溶液。可从反应产物中萃取壬烷化合物和甲醛溶液，并将其回收到工艺中。