Wgv737hbt9 | 2146097-17-6

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 异喹啉及其衍生物
• 英文名称: Wgv737hbt9
• 英文别名: (1S)-1-(1-isoquinolin-5-ylsulfonylpiperidin-4-yl)ethanamine
• CAS: 2146097-17-6
• 化学式: C₁₆H₂₁N₃O₂S
• 分子量: 319.4
• InChiKey: MGLIYKZFLDTAMW-LBPRGKRZSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.5
• 重原子数：
  22
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.44
• 拓扑面积：
  84.7
• 氢给体数：
  1
• 氢受体数：
  5

文献信息

• KINASE INHIBITORS FOR TREATMENT OF DISEASE
  申请人：BioAxone BioSciences, Inc.

  公开号：US20190015404A1

  公开（公告）日：2019-01-17

  Disclosed are therapeutic compositions including BA-1076 and/or BA-2057, methods of their use in the treatment of ophthalmological disorders. The therapeutic compositions may further include an IOP-lowering prostaglandin. The methods may further include administration of an IOP-lowering prostaglandin.
• [EN] KINASE INHIBITORS FOR TREATMENT OF DISEASE<br/>[FR] INHIBITEURS DE KINASE POUR LE TRAITEMENT DE MALADIES
  申请人：BIOAXONE BIOSCIENCES INC

  公开号：WO2019014322A1

  公开（公告）日：2019-01-17

  Disclosed are therapeutic compositions including BA-1076 and/or BA-2057, methods of their use in the treatment of ophthalmological disorders. The therapeutic compositions may further include an IOP- lowering prostaglandin. The methods may further include administration of an lOP-lowering prostaglandin.