N,N-dimethyl-2-(butylthio)ethanamine | 184960-69-8

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: N,N-dimethyl-2-(butylthio)ethanamine
• 英文别名: 2-(Butylsulfanyl)-N,N-dimethylethan-1-amine；2-butylsulfanyl-N,N-dimethylethanamine
• CAS: 184960-69-8
• 化学式: C₈H₁₉NS
• 分子量: 161.312
• InChiKey: JFBUIRIGJZZVBK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.2
• 重原子数：
  10
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  28.5
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  六氟磷酸钾 、 N,N-dimethyl-2-(butylthio)ethanamine 、 以 甲醇 、 水 为溶剂， 生成
  参考文献：
  名称：

  Organometallic ionic liquids from half-sandwich Ru(II) complexes with various chelating ligands

  摘要：

  Salts comprising of cationic half-sandwich Ru(II) complexes with various chelating ligands and the bis (trifluoromethanesulfonyl) amide anion (Tf2N-) were prepared. These salts can be represented as [(arene) RuCl(L-L)][Tf2N] (arene = C6Me5Bu, C6Me6, p-cymene, C6H6; L-L = 2-Py-CH2NHCMe2Et, 2-Py-CH= NC6H13, H13C6NHCH2CH2NHC6H13, Me2NCH2CH2SC4H9, Me2CN=CHCH=NCMe2). Two of the eight salts are liquids at room temperature (similar to 20 degrees C), while the other salts are solids with melting points of 60-130 degrees C. Upon cooling from the melt, most salts exhibited glass transitions between -30 degrees C and -5 degrees C. The salts were found to catalyze the oxidation of cyclohexanol although decomposition occurred during the reaction. Crystal structures of related salts were also determined. (C) 2015 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.ica.2015.09.009

文献信息

• SUBSTITUTED POLYESTERS BY THIOL-ENE MODIFICATION: RAPID DIVERSIFICATION FOR THERAPEUTIC PROTEIN STABILIZATION
  申请人：The Regents of the University of California

  公开号：EP3342796A1

  公开（公告）日：2018-07-04

  Structures and methods of making biodegradable trehalose co-polymers are disclosed. Specifically, biodegradable trehalose co-polymers consist of the general structure R5-[R1R2C - CR3R4]n-[DG]m-R6, wherein R1-R4 are independently selected from hydrogen or a side chain comprising at least one carbon atom, and wherein at least one of R1-R4 is a side chain comprising -L-trehalose, wherein L is a linker molecule that links trehalose to the monomer through at least one of the trehalose hydroxyl groups (-OH), wherein DG is a biodegradable group, and wherein R5 and R6 are end groups.

  本发明公开了可生物降解的三卤糖共聚物的结构和制造方法。具体来说，可生物降解的三卤糖共聚物由一般结构 R5-[R1R2C-CR3R4]n-[DG]m-R6组成，其中 R1-R4 独立地选自氢或包含至少一个碳原子的侧链、其中 R1-R4 中至少有一个是由-L-曲哈糖组成的侧链，其中 L 是连接分子，通过至少一个曲哈糖羟基（-OH）将曲哈糖与单体连接，其中 DG 是可生物降解基团，其中 R5 和 R6 是端基。
• Substituted polyesters by thiol-ene modification: rapid diversification for therapeutic protein stabilization
  申请人：THE REGENTS OF THE UNIVERSITY OF CALIFORNIA

  公开号：US10273333B2

  公开（公告）日：2019-04-30

  Structures and methods of making biodegradable trehalose co-polymers are disclosed. Specifically, biodegradable trehalose co-polymers consist of the general structure R5—[R1R2C—CR3R4]n-[DG]m—R6, wherein R1-R4 are independently selected from hydrogen or a side chain comprising at least one carbon atom, and wherein at least one of R1-R4 is a side chain comprising -L-trehalose, wherein L is a linker molecule that links trehalose to the monomer through at least one of the trehalose hydroxyl groups (—OH), wherein DG is a biodegradable group, and wherein R5 and R6 are end groups.

  本发明公开了可生物降解的三卤糖共聚物的结构和制造方法。具体来说，可生物降解的三卤糖共聚物由一般结构 R5-[R1R2C-CR3R4]n-[DG]m-R6组成，其中 R1-R4 独立地选自氢或包含至少一个碳原子的侧链、其中 R1-R4 中至少有一个是由-L-曲哈糖组成的侧链，其中 L 是连接分子，通过至少一个曲哈糖羟基（-OH）将曲哈糖与单体连接，其中 DG 是可生物降解基团，其中 R5 和 R6 是端基。
• Organometallic ionic liquids from half-sandwich Ru(II) complexes with various chelating ligands
  作者：Takashi Inagaki、Ken-ichi Abe、Kazuyuki Takahashi、Tomoyuki Mochida

  DOI：10.1016/j.ica.2015.09.009

  日期：2015.11

  Salts comprising of cationic half-sandwich Ru(II) complexes with various chelating ligands and the bis (trifluoromethanesulfonyl) amide anion (Tf2N-) were prepared. These salts can be represented as [(arene) RuCl(L-L)][Tf2N] (arene = C6Me5Bu, C6Me6, p-cymene, C6H6; L-L = 2-Py-CH2NHCMe2Et, 2-Py-CH= NC6H13, H13C6NHCH2CH2NHC6H13, Me2NCH2CH2SC4H9, Me2CN=CHCH=NCMe2). Two of the eight salts are liquids at room temperature (similar to 20 degrees C), while the other salts are solids with melting points of 60-130 degrees C. Upon cooling from the melt, most salts exhibited glass transitions between -30 degrees C and -5 degrees C. The salts were found to catalyze the oxidation of cyclohexanol although decomposition occurred during the reaction. Crystal structures of related salts were also determined. (C) 2015 Elsevier B.V. All rights reserved.