[4-methyl-5-(4-oxo-3-o-tolyl-3,4-dihydro-quinazolin-2-yl)-thiazol-2-yl]-carbamic acid ethyl ester | 952612-60-1

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二氮杂萘
• 英文名称: [4-methyl-5-(4-oxo-3-o-tolyl-3,4-dihydro-quinazolin-2-yl)-thiazol-2-yl]-carbamic acid ethyl ester
• 英文别名: ethyl N-[4-methyl-5-[3-(2-methylphenyl)-4-oxoquinazolin-2-yl]-1,3-thiazol-2-yl]carbamate
• CAS: 952612-60-1
• 化学式: C₂₂H₂₀N₄O₃S
• 分子量: 420.492
• InChiKey: WFIVFKLIOUGPBW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.2
• 重原子数：
  30
• 可旋转键数：
  5
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.18
• 拓扑面积：
  112
• 氢给体数：
  1
• 氢受体数：
  6

文献信息

• THIAZOLE AND THIOPHENE ANALOGUES, AND THEIR USE IN TREATING AUTOIMMUNE DISEASES AND CANCERS
  申请人：Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College

  公开号：EP2007393B1

  公开（公告）日：2013-08-21
• Thiazole and Thiophene Analogues, and Their Use in Treating Autoimmune Diseases and Cancers
  申请人：Giordano Anthony

  公开号：US20090306073A1

  公开（公告）日：2009-12-10

  Thiazole and thiophene compounds are disclosed having utility in treating inflammatory conditions, immunoinflammatory conditions, autoimmune diseases, and cancers. Methods for the synthesis of these compounds are also disclosed.
• US8217037B2
  申请人：——

  公开号：US8217037B2

  公开（公告）日：2012-07-10
• US8829014B2
  申请人：——

  公开号：US8829014B2

  公开（公告）日：2014-09-09