2-[[3-(2-fluoroethoxy)phenyl](1-methylpiperidin-4-yloxy)methyl]benzothiazole oxalate | 1370429-17-6

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并噻唑类
• 英文名称: 2-[[3-(2-fluoroethoxy)phenyl](1-methylpiperidin-4-yloxy)methyl]benzothiazole oxalate
• 英文别名: 2-[[3-(2-Fluoroethoxy)phenyl]-(1-methylpiperidin-4-yl)oxymethyl]-1,3-benzothiazole
• CAS: 1370429-17-6
• 化学式: C₂₂H₂₅FN₂O₂S
• 分子量: 400.517
• InChiKey: AMLHXMIZLRUXDO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.7
• 重原子数：
  28
• 可旋转键数：
  7
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.41
• 拓扑面积：
  62.8
• 氢给体数：
  0
• 氢受体数：
  6

文献信息

• Benzazole derivatives as histamine H4 receptor ligands
  申请人：BIOPROJET

  公开号：EP2447263A1

  公开（公告）日：2012-05-02

  The present patent application concerns new ligands of the H4-receptor of formula (I), their process of preparation and their therapeutic use.

  本专利申请涉及公式（I）的H4受体的新配体，它们的制备过程以及它们的治疗用途。
• Benzazole Derivatives as Histamine H4 Receptor Ligands
  申请人：BIOPROJET

  公开号：US20150004181A1

  公开（公告）日：2015-01-01

  The present patent application concerns new ligands of the H4-receptor, their process of preparation and their therapeutic use.

  本专利申请涉及H4受体的新配体，它们的制备过程和治疗用途。
• BENZAZOLE DERIVATIVES AS HISTAMINE H4 RECEPTOR LIGANDS
  申请人：BIOPROJET

  公开号：EP2621916B1

  公开（公告）日：2016-02-10
• H4 RECEPTOR INHIBITORS FOR TREATING TINNITUS
  申请人：Sensorion

  公开号：EP2858647A1

  公开（公告）日：2015-04-15
• PHOTORESIST COMPOSITION, RESIST PATTERN-FORMING METHOD, ACID DIFFUSION CONTROL AGENT, AND COMPOUND
  申请人：JSR CORPORATION

  公开号：US20150004544A1

  公开（公告）日：2015-01-01

  A photoresist composition containing: a polymer including an acid-labile group; a radiation-sensitive acid generator; and an acid diffusion control agent that contains a compound represented by a formula (1). In the formula (1), R 1 , R 2 and R 3 each independently represent a hydrogen atom or a monovalent hydrocarbon group having 1 to 10 carbon atoms. A represents a group having a valency of n that is obtained by combining: a hydrogen atom, a linear hydrocarbon group having 1 to 30 carbon atoms, an alicyclic hydrocarbon group having 3 to 30 carbon atoms or a combination thereof; —O—, —CO—, —COO—, —SO 2 O—, —NRSO 2 —, —NRSO 2 O—, —NRCO— or a combination thereof; and n nitrogen atoms as a binding site to the carbonyl group in the formula (1), in which a sum of atomic masses of the atoms constituting A is no less than 120. n is an integer of 1 to 4.