(1R,2S,4aS,4bS,7S,8aS,10aR)-7-Methoxymethoxy-1-((R)-1-methoxymethoxy-5-methyl-hex-2-ynyl)-2,4b-dimethyl-tetradecahydro-phenanthrene-2-carbaldehyde | 210641-92-2

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 类固醇和类固醇衍生物
• 英文名称: (1R,2S,4aS,4bS,7S,8aS,10aR)-7-Methoxymethoxy-1-((R)-1-methoxymethoxy-5-methyl-hex-2-ynyl)-2,4b-dimethyl-tetradecahydro-phenanthrene-2-carbaldehyde
• CAS: 210641-92-2
• 化学式: C₂₈H₄₆O₅
• 分子量: 462.67
• InChiKey: HYDWBTCGEYDWMM-GOMSDNTOSA-N

反应信息

• 作为反应物：
  描述：

  (1R,2S,4aS,4bS,7S,8aS,10aR)-7-Methoxymethoxy-1-((R)-1-methoxymethoxy-5-methyl-hex-2-ynyl)-2,4b-dimethyl-tetradecahydro-phenanthrene-2-carbaldehyde 在 正丁基锂 作用下， 以 二氯甲烷 为溶剂， 反应 20.42h， 生成 1-((3S,5S,8R,9S,10S,13S,14R,15R)-3,15-Bis-methoxymethoxy-10,13,17-trimethyl-2,3,4,5,6,7,8,9,10,11,12,13,14,15-tetradecahydro-1H-cyclopenta[a]phenanthren-16-yl)-3-methyl-butan-1-one
  参考文献：
  名称：

  Synthesis of the pentacyclic xestobergsterol skeleton

  摘要：

  An approach to the synthesis of the histamine release inhibitor xestobergsterol is described. The intramolecular Pauson-Khand reaction was used to generate the D and E rings of the steroid. (C) 1998 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4020(98)00345-7
• 作为产物：
  描述：

  [(1R,2S,4aS,4bS,7S,8aS,10aR)-7-Methoxymethoxy-1-((R)-1-methoxymethoxy-5-methyl-hex-2-ynyl)-2,4b-dimethyl-tetradecahydro-phenanthren-2-yl]-methanol 在 四丙基高钌酸铵 、 氧化-4-甲基吗啉一水合物 作用下， 以 二氯甲烷 为溶剂， 反应 1.0h， 以90%的产率得到(1R,2S,4aS,4bS,7S,8aS,10aR)-7-Methoxymethoxy-1-((R)-1-methoxymethoxy-5-methyl-hex-2-ynyl)-2,4b-dimethyl-tetradecahydro-phenanthrene-2-carbaldehyde
  参考文献：
  名称：

  Synthesis of the pentacyclic xestobergsterol skeleton

  摘要：

  An approach to the synthesis of the histamine release inhibitor xestobergsterol is described. The intramolecular Pauson-Khand reaction was used to generate the D and E rings of the steroid. (C) 1998 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4020(98)00345-7