2,5-dimethylhexane-2,5-diisocyanate | 45128-93-6

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: 2,5-dimethylhexane-2,5-diisocyanate
• 英文别名: 2,5-Diisocyanato-2,5-dimethylhexane
• CAS: 45128-93-6
• 化学式: C₁₀H₁₆N₂O₂
• 分子量: 196.249
• InChiKey: CREYJURAGBVAMX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.7
• 重原子数：
  14
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.8
• 拓扑面积：
  58.9
• 氢给体数：
  0
• 氢受体数：
  4

文献信息

• Polycyclische Iminooxadiazindione aus (cyclo)aliphatischen 1,4-Diisocyanaten
  申请人：BAYER AG

  公开号：EP0849268A1

  公开（公告）日：1998-06-24

  Die Erfindung betrifft polycyclische Iminooxadiazindione aus (cyclo)aliphatischen 1,4-Diisocyanaten.

  本发明涉及由（环）脂肪族 1,4-二异氰酸酯制成的多环亚氨基恶二嗪二iones。
• Wound dressings and applications thereof
  申请人：THE PENN STATE RESEARCH FOUNDATION

  公开号：US11173227B2

  公开（公告）日：2021-11-16

  In one aspect, compositions and wound dressings are described herein. In some embodiments, a composition or wound dressing described herein comprises a mesh formed from a plurality of biodegradable polymer fibers; a first active agent dispersed in the biodegradable polymer fibers; a plurality of biodegradable polymer particles disposed in the mesh; and a second active agent dispersed in the biodegradable polymer particles. The particles can be disposed within the interiors of the fibers of the mesh or between the fibers of the mesh. In another aspect, a composition or wound dressing described herein comprises a first perforated mesh formed from a first plurality of biodegradable polymer fibers; and a second perforated mesh formed from a second plurality of biodegradable polymer fibers, wherein the second perforated mesh is disposed on the first perforated mesh in a stacked configuration and the first and second perforated meshes have different degrees of perforation.

  一方面，本文描述了组合物和伤口敷料。在一些实施方案中，本文所述的组合物或伤口敷料包括由多种可生物降解聚合物纤维形成的网状物；分散在可生物降解聚合物纤维中的第一活性剂；分散在网状物中的多种可生物降解聚合物颗粒；以及分散在可生物降解聚合物颗粒中的第二活性剂。颗粒可以放置在网眼纤维的内部或网眼纤维之间。在另一方面，本文所述的组合物或伤口敷料包括由第一种多种可生物降解聚合物纤维形成的第一穿孔网；以及由第二种多种可生物降解聚合物纤维形成的第二穿孔网，其中第二穿孔网以堆叠配置的方式布置在第一穿孔网上，且第一和第二穿孔网具有不同的穿孔度。
• Halogenierte, tertiäre Alkylisocyanate und Verfahren zu ihrer Herstellung
  申请人：BASF Aktiengesellschaft

  公开号：EP0025907B1

  公开（公告）日：1984-06-20
• Compositions Comprising Citrate and Applications Thereof
  申请人：Board of Regents, The University of Texas System

  公开号：US20190247424A1

  公开（公告）日：2019-08-15

  In one aspect, methods of promoting bone growth are described herein. In some embodiments, a method of promoting bone growth described herein comprises promoting cell differentiation or phenotype progression in a population of bone cells by providing a citrate-presenting composition to the population of bone cells. In some embodiments, the citrate-presenting composition is provided to the bone cells at a first stage of cell development selected to obtain a first cell differentiation or phenotype progression. Additionally, in some cases, a second citrate-presenting composition is further provided to the bone cells at a second stage of cell development selected to obtain a second cell differentiation or phenotype progression.
• Imaging Compositions
  申请人：THE PENN STATE RESEARCH FOUNDATION

  公开号：US20190282713A1

  公开（公告）日：2019-09-19

  In one aspect, compositions are described herein. In some embodiments, a composition described herein comprises, consists of, or consists essentially of an MRI-active or MRI-sensitive polymer or oligomer formed from (i) a non-alkoxylated and non-alkenoxylated citric acid, citrate, or ester/amide of citric acid, and optionally an alkoxylated or alkenoxylated citric acid, citrate, or ester/amide of citric acid, (ii) a polyol/polyamine such as a diol/diamine, (iii) a monomer comprising an MRI contrast agent, and (iv) an amino acid monomer. The polymer or oligomer may be photoluminescent and MRI-sensitive. In another aspect, imaging methods utilizing the compositions described herein are described. In another aspect, scaffolds, grafts, and films comprising, consisting of, or consisting essentially of the compositions described herein are described.