3α-hydroxy-10.13.17β-trimethyl-5α-gonane | 94841-11-9

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 类固醇和类固醇衍生物
• 英文名称: 3α-hydroxy-10.13.17β-trimethyl-5α-gonane
• 英文别名: (10S)-3t-Hydroxy-10r.13c.17c-trimethyl-(5tH.8cH.9tH.14tH)-hexadecahydro-1H-cyclopenta[a]phenanthren；3α-Hydroxy-10.13.17β-trimethyl-5α-gonan；(3R,5S,8S,9S,10S,13R,14S,17S)-10,13,17-trimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol
• CAS: 94841-11-9
• 化学式: C₂₀H₃₄O
• 分子量: 290.489
• InChiKey: DFRCKGPGVYYUQO-HUJIKHNRSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.2
• 重原子数：
  21
• 可旋转键数：
  0
• 环数：
  4.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  3α-hydroxy-10.13.17β-trimethyl-5α-gonane 生成 5a-雄甾烷-3a,17b-二醇
  参考文献：
  名称：

  GRIECO, PAUL A.;STUK, TIMOTHY L., J. AMER. CHEM. SOC., 112,(1990) N1, C. 7799-7801

  摘要：

  DOI：
• 作为产物：
  描述：

  (3α,5α)-17-methylene-androstan-3-ol 在 乙醇 、 铂 作用下， 生成 3α-hydroxy-10.13.17β-trimethyl-5α-gonane
  参考文献：
  名称：

  Facilitating Children's Understanding of Misinterpretation: Explanatory Efforts and Improvements in Perspective Taking

  摘要：

  The authors investigated children's understanding of how mistaken beliefs can arise through misinterpretation of ambiguous information. Children (N = 91), aged 4 to 5 years, were given pre- and posttests on their ability to infer a puppet's interpretation of a restricted-view drawing after the puppet had been led to an erroneous expectation about the drawing's identity. Before the posttest, the children received either self-explanation training or other-explanation training in which they explained the source of their own or a puppet's misinterpretations of drawings; a control group received no training. The children who received training improved from pre- to posttest, and those who had practiced explaining misinterpretations by referring to previously viewed pictures or to features of a target picture showed the greatest improvement. These results indicate that learning to explain misinterpretations can help children recognize situations in which misinterpretations are likely to occur.

  DOI：

  10.1080/00221320209598673

文献信息

• METHOD AND KIT FOR SUPER-HIGH-SENSITIVITY MEASUREMENT OF PROTEIN AND NUCLEIC ACID, AND NOVEL ENZYME SUBSTRATE
  申请人：Ito, Etsuro

  公开号：EP3296405A1

  公开（公告）日：2018-03-21

  Provided is a ultra-high-sensitivity assay in which the assay can be made on a commonly used assay apparatus such as an absorptiometer and a plate reader or with naked eyes. The high-sensitivity assay in which the assay can be made on a commonly used assay apparatus or with naked eyes can be provided by combining an enzyme cycling method using thio-NAD(P) as a coenzyme, a labeling enzyme and a substrate for the labeling enzyme optimally, and by amplifying thio-NAD(P)H, which is a signaling substance, exponentially and then quantifying the thio-NAD(P)H colorimetrically.

  本发明提供了一种超高灵敏度检测方法，该方法可在常用的检测仪器（如吸收仪和平板阅读器）上或用肉眼进行检测。通过优化组合使用硫代-NAD(P)作为辅酶的酶循环方法、标记酶和标记酶底物，并通过指数放大作为信号物质的硫代-NAD(P)H，然后用比色法对硫代-NAD(P)H进行定量，可提供可在常用检测仪器上或用肉眼进行检测的高灵敏度检测方法。
• Ultra-high-sensitive assay of protein and nucleic acid and kit, and novel enzyme substrate
  申请人：Ito Etsuro

  公开号：US11221299B2

  公开（公告）日：2022-01-11

  Provided is a ultra-high-sensitivity assay in which the assay can be made on a commonly used assay apparatus such as an absorptiometer and a plate reader or with naked eyes. The high-sensitivity assay in which the assay can be made on a commonly used assay apparatus or with naked eyes can be provided by combining an enzyme cycling method using thio-NAD(P) as a coenzyme, a labeling enzyme and a substrate for the labeling enzyme optimally, and by amplifying thio-NAD(P)H, which is a signaling substance, exponentially and then quantifying the thio-NAD(P)H colorimetrically.

  本发明提供了一种超高灵敏度检测方法，该方法可在常用的检测仪器（如吸收仪和平板阅读器）上或用肉眼进行检测。通过优化组合使用硫代-NAD(P)作为辅酶的酶循环方法、标记酶和标记酶底物，并通过指数放大作为信号物质的硫代-NAD(P)H，然后用比色法对硫代-NAD(P)H进行定量，可提供可在常用检测仪器上或用肉眼进行检测的高灵敏度检测方法。
• Method and kit for super-high-sensitivity measurement of protein and nucleic acid, and novel enzyme substrate
  申请人：Ito, Etsuro

  公开号：EP2695948B1

  公开（公告）日：2016-12-28
• ULTRA-HIGH-SENSITIVE ASSAY OF PROTEIN AND NUCLEIC ACID AND KIT, AND NOVEL ENZYME SUBSTRATE
  申请人：ITO Etsuro

  公开号：US20180106727A1

  公开（公告）日：2018-04-19

  Provided is a ultra-high-sensitivity assay in which the assay can be made on a commonly used assay apparatus such as an absorptiometer and a plate reader or with naked eyes. The high-sensitivity assay in which the assay can be made on a commonly used assay apparatus or with naked eyes can be provided by combining an enzyme cycling method using thio-NAD(P) as a coenzyme, a labeling enzyme and a substrate for the labeling enzyme optimally, and by amplifying thio-NAD(P)H, which is a signaling substance, exponentially and then quantifying the thio-NAD(P)H colorimetrically.