4-sec-Hexyl-2-chlor-phenol | 22702-54-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 酚类
• 英文名称: 4-sec-Hexyl-2-chlor-phenol
• 英文别名: 2-Chloro-4-hexan-2-ylphenol
• CAS: 22702-54-1
• 化学式: C₁₂H₁₇ClO
• 分子量: 212.719
• InChiKey: HXZSSISUMMJAEZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.9
• 重原子数：
  14
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  1

文献信息

• PPAR agonists
  申请人：Salk Institute for Biological Studies

  公开号：US11420934B2

  公开（公告）日：2022-08-23

  Provided herein are compounds and compositions useful in increasing PPARδ activity. The compounds and compositions provided herein are useful for the treatment of PPARδ related diseases (e.g., muscular diseases, vascular disease, demyelinating disease, and metabolic diseases).

  本文提供的是有助于提高 PPARδ 活性的化合物和组合物。本文提供的化合物和组合物可用于治疗 PPARδ 相关疾病（如肌肉疾病、血管疾病、脱髓鞘疾病和代谢性疾病）。
• PPAR AGONISTS
  申请人：Salk Institute for Biological Studies

  公开号：US20200190019A1

  公开（公告）日：2020-06-18

  Provided herein are compounds and compositions useful in increasing PPARδ activity. The compounds and compositions provided herein are useful for the treatment of PPARδ related diseases (e.g., muscular diseases, vascular disease, demyelinating disease, and metabolic diseases).
• PYRAZOLO AND TRIAZOLO BICYCLIC COMPOUNDS AS JAK KINASE INHIBITORS
  申请人：THERAVANCE BIOPHARMA R&D IP, LLC

  公开号：US20220119369A1

  公开（公告）日：2022-04-21

  The invention provides compounds of formula (I): or a pharmaceutically-acceptable salt thereof, wherein the variables are defined in the specification, that are inhibitors of JAK kinases, particularly JAK3. The invention also provides crystalline forms, pharmaceutical compositions comprising such compounds, methods of using such compounds to treat gastrointestinal and other inflammatory diseases, and processes and intermediates useful for preparing such compounds.