methyl 6-({4'-[2-ethoxy-2-(5-propyl-[1,3,4]oxadiazol-2-yl)ethyl]biphenyl-3-ylmethyl}methylcarbamoyl)naphthalene-2-carboxylate | 692780-77-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: methyl 6-({4'-[2-ethoxy-2-(5-propyl-[1,3,4]oxadiazol-2-yl)ethyl]biphenyl-3-ylmethyl}methylcarbamoyl)naphthalene-2-carboxylate
• 英文别名: Methyl 6-[[3-[4-[2-ethoxy-2-(5-propyl-1,3,4-oxadiazol-2-yl)ethyl]phenyl]phenyl]methyl-methylcarbamoyl]naphthalene-2-carboxylate
• CAS: 692780-77-1
• 化学式: C₃₆H₃₇N₃O₅
• 分子量: 591.707
• InChiKey: CHLKXJPJESHSCZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.7
• 重原子数：
  44
• 可旋转键数：
  13
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.28
• 拓扑面积：
  94.8
• 氢给体数：
  0
• 氢受体数：
  7

文献信息

• Novel biaromatic compounds which activate PPARgamma type receptors and cosmetic/pharmaceutical compositions comprised thereof
  申请人：Clary Laurence

  公开号：US20060004048A1

  公开（公告）日：2006-01-05

  Novel biaromatic compounds having the structural formula (I) below: are formulated into pharmaceutical compositions suited for administration in human or veterinary medicine (in dermatology, and also in the fields of cardiovascular diseases, immune diseases and/or diseases associated with lipid metabolism), or, alternatively, into cosmetic compositions.

  具有以下结构式（I）的新型双芳香化合物被制成适用于人类或兽医药物的制剂（在皮肤科，以及心血管疾病，免疫疾病和/或与脂质代谢有关的疾病领域），或者，制成化妆品制剂。
• Novel biaromatic compounds which activate PPARy type receptors and cosmetic/pharmaceutical compositions comprised thereof
  申请人：Clary Laurence

  公开号：US20080070957A1

  公开（公告）日：2008-03-20

  Novel biaromatic compounds having the structural formula (I) below: are formulated into pharmaceutical compositions suited for administration in human or veterinary medicine (in dermatology, and also in the fields of cardiovascular diseases, immune diseases and/or diseases associated with lipid metabolism), or, alternatively, into cosmetic compositions.

  具有以下结构式（I）的新型双芳香族化合物被制成适用于人类或兽医药物（在皮肤科以及心血管疾病、免疫性疾病和/或与脂质代谢相关的疾病领域）的制剂，或者是化妆品制剂。
• US7285568B2
  申请人：——

  公开号：US7285568B2

  公开（公告）日：2007-10-23
• US7582663B2
  申请人：——

  公开号：US7582663B2

  公开（公告）日：2009-09-01