4-bromo-N-[(2-bromophenyl)-[diethoxy(oxido)phosphaniumyl]methyl]aniline | 1433901-25-7

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: 4-bromo-N-[(2-bromophenyl)-[diethoxy(oxido)phosphaniumyl]methyl]aniline
• CAS: 1433901-25-7
• 化学式: C₁₇H₂₀Br₂NO₃P
• 分子量: 477.132
• InChiKey: UMMUPLQXUVTFHU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.9
• 重原子数：
  24
• 可旋转键数：
  8
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.29
• 拓扑面积：
  53.6
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  磷酸三乙酯 、 邻溴苯甲醛 、 4-溴苯胺 在 phosphotungstic acid supported on imidazole functionalized silica coated cobalt ferrite nanoparticle 作用下， 以 neat (no solvent) 为溶剂， 反应 0.5h， 以89%的产率得到4-bromo-N-[(2-bromophenyl)-[diethoxy(oxido)phosphaniumyl]methyl]aniline
  参考文献：
  名称：

  Magnetic nanoparticle supported polyoxometalate: An efficient and reusable catalyst for solvent-free synthesis of α-aminophosphonates

  摘要：

  A new magnetically separable catalyst consisting of phosphotungstic acid (PTA) supported on imidazole functionalized silica coated cobalt ferrite nanoparticles was prepared. The synthesized catalyst was characterized by X-ray powder diffraction (XRD), transmission electron microscopy (TEM), vibrating sample magnetometry (VSM), thermogravimetric analysis (TGA), Fourier transform infrared (FT-IR), and inductively coupled plasma atomic emission spectroscopy (ICP-AES). The immobilized phosphotungstic acid was shown to be an efficient heterogeneous catalyst for the synthesis of alpha-aminophosphonates under solvent-free conditions at room temperature. The catalyst is readily recovered by simple magnetic decantation and can be recycled several times with no significant loss of catalytic activity. (C) 2013 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.molcata.2013.02.018

文献信息

• Supported sulfonic acid on magnetic nanoparticles used as a reusable catalyst for rapid synthesis of <b>α</b>-aminophosphonates
  作者：Mozhgan Afshari、Maryam Gorjizadeh、Mohammad Naseh

  DOI：10.1080/15533174.2016.1186096

  日期：2017.4.3

  Sulfonic acid was anchored on the surface of silica-coated cobalt ferrite core to obtain a new magnetically separable catalyst. The resultant composite was characterized by various techniques, including FT-IR, X-ray diffraction, FESEM, energy-dispersive X-ray, TEM, TGA, and vibrating sample magnetometer. The immobilized sulfonic acid was shown to be an efficient heterogeneous catalyst for the synthesis

  磺酸被锚固在二氧化硅涂层的钴铁氧体磁芯的表面上，从而获得了一种新型的可磁分离的催化剂。所得复合材料通过多种技术进行表征，包括FT-IR，X射线衍射，FESEM，能量色散X射线，TEM，TGA和振动样品磁力计。固定化的磺酸是在室温下无溶剂条件下合成α-氨基膦酸酯的有效多相催化剂。通过简单的磁倾析可以很容易地回收催化剂，并且可以循环使用7次，而不会明显降低催化活性。
• Niobium pentoxide, a recyclable heterogeneous solid surface catalyst for the synthesis of α-amino phosphonates
  作者：Anita Sahani、Ramana Sreenivasa Rao、Adithya Vadakkayil、Murugesan Santhosh、Mahalingam Mummoorthi、Muthupandi Karthick、Chinnasamy Ramaraj Ramanathan

  DOI：10.1007/s12039-020-01853-7

  日期：2021.3

  Abstract Niobium pentoxide, a bifunctional solid surface catalyst, has been successfully employed to facilitate the three-component reaction between aldehydes, amines and triethyl phosphite at room temperature under solvent-free conditions to generate α-amino phosphonate in moderate to good yields. The catalyst can be recycled through simple filtration and reused to effect this transformation. Graphic

  摘要 五氧化铌是一种双功能固体表面催化剂，已成功地用于促进醛，胺和亚磷酸三乙酯之间在室温下在无溶剂条件下的三组分反应，从而以中等至良好的产率生成α-氨基膦酸酯。催化剂可以通过简单的过滤进行再循环，然后再重复使用以实现这种转化。 图形摘要
• Magnetic nanoparticle supported polyoxometalate: An efficient and reusable catalyst for solvent-free synthesis of α-aminophosphonates
  作者：H. Hamadi、M. Kooti、M. Afshari、Z. Ghiasifar、N. Adibpour

  DOI：10.1016/j.molcata.2013.02.018

  日期：2013.7

  A new magnetically separable catalyst consisting of phosphotungstic acid (PTA) supported on imidazole functionalized silica coated cobalt ferrite nanoparticles was prepared. The synthesized catalyst was characterized by X-ray powder diffraction (XRD), transmission electron microscopy (TEM), vibrating sample magnetometry (VSM), thermogravimetric analysis (TGA), Fourier transform infrared (FT-IR), and inductively coupled plasma atomic emission spectroscopy (ICP-AES). The immobilized phosphotungstic acid was shown to be an efficient heterogeneous catalyst for the synthesis of alpha-aminophosphonates under solvent-free conditions at room temperature. The catalyst is readily recovered by simple magnetic decantation and can be recycled several times with no significant loss of catalytic activity. (C) 2013 Elsevier B.V. All rights reserved.