Androst-5-ene-3,11,17-trione | 10338-37-1

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 类固醇和类固醇衍生物
• 英文名称: Androst-5-ene-3,11,17-trione
• 英文别名: (8S,9S,10R,13S,14S)-10,13-dimethyl-1,2,4,7,8,9,12,14,15,16-decahydrocyclopenta[a]phenanthrene-3,11,17-trione
• CAS: 10338-37-1
• 化学式: C₁₉H₂₄O₃
• 分子量: 300.4
• InChiKey: KIEUSUVLMCIWSA-IRIMSJTPSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.3
• 重原子数：
  22
• 可旋转键数：
  0
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.74
• 拓扑面积：
  51.2
• 氢给体数：
  0
• 氢受体数：
  3

文献信息

• Steroids and therapeutic compositions containing same
  申请人：RESEARCH CORPORATION TECHNOLOGIES, INC.

  公开号：EP0133995A2

  公开（公告）日：1985-03-13

  Steroids of the formula and a therapeutic composition containing same which are useful as anti-cancer, anti-obesity, anti-hyperglycemic, anti-autoimmune and anti-hypercholesterolemic agents.

  式中的类固醇 以及含有这些物质的治疗组合物，可用作抗癌、抗肥胖、抗高血糖、抗自身免疫和抗高胆固醇血症的药物。
• Steroids useful as anti-cancer and anti-obesity agents, a therapeutic composition containing them and use thereof for the preparation of a therapeutic composition
  申请人：RESEARCH CORPORATION TECHNOLOGIES, INC.

  公开号：EP0246650B1

  公开（公告）日：1992-01-02
• Methods and systems for the quantitative analysis of biomarkers
  申请人：Grant Russell Philip

  公开号：US20080128606A1

  公开（公告）日：2008-06-05

  Disclosed are methods and systems using liquid chromatography/tandem mass spectrometry (LC-MS/MS and 2D-LC-MS/MS) for the analysis of endogenous biomarkers, including steroid hormones, such as estrone and estradiol, thyroid hormones, such as free thyroxine, and metabolites, such as 25-hydroxyvitamin D2 and 25-hydroxyvitamin D3, in biological samples.
• Methods and Systems for the Quantitative Analysis of Biomarkers
  申请人：Grant Russell Philip

  公开号：US20110240842A1

  公开（公告）日：2011-10-06

  Disclosed are methods and systems using liquid chromatography/tandem mass spectrometry (LC-MS/MS and 2D-LC-MS/MS) for the analysis of endogenous biomarkers, including steroid hormones, such as estrone and estradiol, thyroid hormones, such as free thyroxine, and metabolites, such as 25-hydroxyvitamin D2 and 25-hydroxyvitamin D3, in biological samples.
• US4898694A
  申请人：——

  公开号：US4898694A

  公开（公告）日：1990-02-06