4,8-Diaza-2,10-undecandiamin | 36748-48-8

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: 4,8-Diaza-2,10-undecandiamin
• 英文别名: 4,8-Diaza-2,10-undecanediamine；1-N-[3-(2-aminopropylamino)propyl]propane-1,2-diamine
• CAS: 36748-48-8
• 化学式: C₉H₂₄N₄
• 分子量: 188.316
• InChiKey: GAQVEOMWFGQAPS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.3
• 重原子数：
  13
• 可旋转键数：
  8
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  76.1
• 氢给体数：
  4
• 氢受体数：
  4

文献信息

• Cationic polymers having degradable crosslinks
  申请人：Li Sheng

  公开号：US20050089503A1

  公开（公告）日：2005-04-28

  A synthetic polymer comprises a cationic recurring unit and a crosslinking unit, wherein the crosslinking unit comprises at least a first degradable unit (preferably acid-labile) and at least a second degradable unit (preferably hydrolyzable). A carrier composition comprising the synthetic polymer and a bioactive agent is useful for the delivery of the bioactive agent into the nuclei of the cells.

  合成聚合物包括一个阳离子重复单元和一个交联单元，其中交联单元包括至少一个可降解单元（最好是酸可降解的）和至少一个可降解单元（最好是水解的）。包括合成聚合物和生物活性剂的载体组合物可用于将生物活性剂传递到细胞核中。
• A method for producing aryl alkyl hydroperoxides
  申请人：MITSUI PETROCHEMICAL INDUSTRIES, LTD.

  公开号：EP0729938A2

  公开（公告）日：1996-09-04

  A method for producing aryl alkyl hydroperoxides which comprises selectively oxidizing an aryl alkyl hydrocarbon having the formula: wherein P and Q are hydrogen or an alkyl and may be the same or different from each other; x is an integer of 1-3; and Ar is an aromatic hydrocarbon group having a valence of x, with an oxygen-containing gas in the presence of a transition metal complex which contains, as a ligand, a cyclic polyfunctional amine compound having at least three nitrogen atoms in the ring forming molecular chain or an open chain polyfunctional amine compound having at least three nitrogen atoms in the main chain of the molecule.

  一种生产芳基烷基氢过氧化物的方法，包括选择性地氧化具有以下式子的芳基烷基碳氢化合物： 其中P和Q是氢或烷基，可以相同或不同；x是1-3的整数；Ar是化合价为x的芳香烃基团，在过渡金属配合物存在下，用含氧气体氧化，过渡金属配合物作为配体，含有在成环分子链中至少有三个氮原子的环状多官能胺化合物或在分子主链中至少有三个氮原子的开链多官能胺化合物。
• Intracellular peptide delivery
  申请人：Minomi Kenjiro

  公开号：US20060083737A1

  公开（公告）日：2006-04-20

  Methods and kits for transporting heterologous compounds into cells, particularly mammalian cells, are disclosed. The method involves the pretreatment of the cell with a polycation, cationic polymer and/or cationic peptide before transportation of the heterologous compound into the cell. The methods are particularly applicable to the transport of peptides and proteins.

  本发明公开了将异源化合物转运入细胞，特别是哺乳动物细胞的方法和试剂盒。该方法包括在将异源化合物转运入细胞前，先用多阳离子、阳离子聚合物和/或阳离子肽对细胞进行预处理。这些方法尤其适用于多肽和蛋白质的运输。
• CATIONIC POLYMERS HAVING DEGRADABLE CROSSLINKS
  申请人：NITTO DENKO CORPORATION

  公开号：EP1675888A1

  公开（公告）日：2006-07-05
• INTRACELLULAR PEPTIDE DELIVERY
  申请人：NITTO DENKO CORPORATION

  公开号：EP1812074A1

  公开（公告）日：2007-08-01