5-(4-hydroxy-3-methoxy-benz-(Z)-ylidene)-2-[(Z)-propylimino]-3-(2-chlorophenyl)-thiazolidin-4-one | 1029435-64-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 酚类
• 英文名称: 5-(4-hydroxy-3-methoxy-benz-(Z)-ylidene)-2-[(Z)-propylimino]-3-(2-chlorophenyl)-thiazolidin-4-one
• CAS: 1029435-64-0
• 化学式: C₂₀H₁₉ClN₂O₃S
• 分子量: 402.901
• InChiKey: OVDVKRAHIJHLRM-CXDOZEDNSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.94
• 重原子数：
  27.0
• 可旋转键数：
  5.0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  62.13
• 氢给体数：
  1.0
• 氢受体数：
  5.0

文献信息

• NEW PROCESS FOR THE PREPARATION OF 2-IMINO-THIAZOLIDIN-4-ONE DERIVATIVES
  申请人：Abele Stefan

  公开号：US20100317867A1

  公开（公告）日：2010-12-16

  The present invention relates to a new process for the preparation of 2-imino-thiazolidin-4-one compounds of the Formula (I) and (II) and to compounds of Formula (II) as such. The present compounds of Formula (II) can be used as intermediates in the preparation of thiazolidin-4-one derivatives of the General Formula (II), said derivatives being described in WO 2005/054215. These compounds of General Formula (II) are described in WO 2005/054215 to act as immunosuppressive agents.
• NEW PROCESS FOR THE PREPARATION OF 2-IMINO-THIAZOLIDIN-4-ONE DERIVATES
  申请人：Abele Stefan

  公开号：US20110201821A2

  公开（公告）日：2011-08-18

  The present invention relates to a new process for the preparation of 2-imino-thiazolidin-4-one compounds of the Formula (I) and (II) and to compounds of Formula (II) as such. The present compounds of Formula (II) can be used as intermediates in the preparation of thiazolidin-4-one derivatives of the General Formula (II), said derivatives being described in WO 2005/054215. These compounds of General Formula (II) are described in WO 2005/054215 to act as immunosuppressive agents.
• US8263780B2
  申请人：——

  公开号：US8263780B2

  公开（公告）日：2012-09-11
• US8912340B2
  申请人：——

  公开号：US8912340B2

  公开（公告）日：2014-12-16