meso-2,4-dimethylcadaverine | 44815-61-4

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: meso-2,4-dimethylcadaverine
• 英文别名: (+/-)-1,5-Diamino-2,4-dimethylpentan；1,5-Diamino-2,4-dimethylpentane；2,4-dimethylpentane-1,5-diamine
• CAS: 44815-61-4
• 化学式: C₇H₁₈N₂
• mdl: MFCD19206444
• 分子量: 130.233
• InChiKey: AJMALXBRSCPCJC-UHFFFAOYSA-N

物化性质

• 沸点：
  189.1±8.0 °C(Predicted)
• 密度：
  0.855±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  0.3
• 重原子数：
  9
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  52
• 氢给体数：
  2
• 氢受体数：
  2

文献信息

• [EN] HIV INTEGRASE INHIBITORY OXOISOINDOLINE SULFONAMIDES<br/>[FR] OXOISOINDOLINE SULFONAMIDES INHIBITEURS DE L'INTÉGRASE DU VIH
  申请人：US OF AMERICA REPRESENTED BY THE SECRETARY DEPT OF HEALTH & HUMAN SERVICES

  公开号：WO2013016441A1

  公开（公告）日：2013-01-31

  Novel oxoisoindoline sulfonamide integrase inhibitors are useful to inhibit HIV activity, and are therefore suitable for treatment or prophylaxis of HIV infection, for example in the treatment or prevention of AIDS. In particular embodiments, the inhibitors are oxoisoindoline-4- sulfonamides, such as 6,7- dihydroxy- 1 -oxoisomdolirie-4-sulfonamides.

  新型的氧代异吲哚磺胺整合酶抑制剂对于抑制HIV活性非常有用，因此适用于治疗或预防HIV感染，例如用于治疗或预防艾滋病。在特定实施方式中，这些抑制剂是氧代异吲哚-4-磺胺，如6,7-二羟基-1-氧代异吲哚-4-磺胺。
• NOVEL POLYAMINE ANALOG CONJUGATES AND QUINONE CONJUGATES AS THERAPIES FOR CANCERS AND PROSTATE DISEASES
  申请人：Frydman Benjamin

  公开号：US20080194697A1

  公开（公告）日：2008-08-14

  Peptide conjugates in which cytostatic and cytostatic agents, such as polyamine analogs or naphthoquinones, are conjugated to a polypeptide recognized and cleaved by enzymes such as prostate-specific antigen (PSA) and cathepsin B are provided, as well as compositions comprising these conjugates. Methods of using these conjugates in the treatment of prostate diseases are also provided.

  提供了肽共轭物，其中细胞生长抑制剂和细胞毒剂，如多胺类似物或萘醌，与多肽共轭，并被酶如前列腺特异性抗原（PSA）和半胱氨酸蛋白酶B识别和剪切，以及包含这些共轭物的组合物。还提供了使用这些共轭物治疗前列腺疾病的方法。
• CONDUCTING AND SEMICONDUCTING ORGANIC MATERIALS
  申请人：Commonwealth Scientific and Industrial Research Organisation

  公开号：US20130289217A1

  公开（公告）日：2013-10-31

  A polymer comprising a conducting or semiconducting segment coupled to a polymer segment having an insulating polymer backbone, the polymer further comprising a RAFT functional group coupled to the polymer segment, wherein there is no RAFT functional group in between the conducting or semiconducting segment and the polymer segment.

  一种聚合物，包括一个导电或半导体段与一个具有绝缘聚合物骨架的聚合物段相耦合，该聚合物进一步包括与聚合物段相耦合的RAFT功能基团，其中在导电或半导体段与聚合物段之间没有RAFT功能基团。
• POLYAMIDE AND POLYAMIDE COMPOSITION
  申请人：Asahi Kasei Chemicals Corporation

  公开号：EP2476717A1

  公开（公告）日：2012-07-18

  [Problem to be Solved] To provide a polyamide having a high melting point, which has excellent strength, toughness, and stability under heating. [Solution] This polyamide is obtained by polymerizing an (a) dicarboxylic acid comprising at least 50 mol% of an alicyclic dicarboxylic acid and a (b) diamine comprising at least 50 mol% of a diamine having a pentamethylenediamine skeleton, wherein the polyamide has a cyclic amino end amount of 30 to 60 µ equivalents/g.

  [有待解决的问题］ 提供一种具有高熔点的聚酰胺，它在加热条件下具有优异的强度、韧性和稳定性。 [解决方案］ 这种聚酰胺是通过聚合(a)二羧酸和(b)二胺得到的，(a)二羧酸包括至少 50 摩尔%的脂环族二羧酸，(b)二胺包括至少 50 摩尔%的具有五亚甲二胺骨架的二胺，其中聚酰胺的环氨基端量为 30 至 60 µ当量/克。
• Enzymatic synthesis of polyamide in aqueous mini-emulsion
  申请人：Henkel AG & Co. KGaA

  公开号：EP2738198A1

  公开（公告）日：2014-06-04

  A process for preparing an aqueous polyamide dispersion, said process comprising reacting in an aqueous medium: a) an organic diamine compound (A) and b) an organic dicarboxylic acid compound (B), in the presence of c) at least one hydrolase enzyme (C) which catalyzes a polycondensation reaction of the diamine compound (A) and dicarboxylic acid compound (B) and d) an emulsifier (D), said process being characterized in that at least a fraction of the diamine compound (A) and the dicarboxylic acid compound (B) are provided in the aqueous medium as a disperse phase having an average droplet diameter of from 40 to 500nm.

  一种制备水性聚酰胺分散体的工艺，所述工艺包括在水性介质中使以下物质发生反应a) 有机二胺化合物 (A) 和 b) 有机二羧酸化合物 (B)，同时存在 c) 至少一种水解酶 (C)，该酶可催化二胺化合物 (A) 和二羧酸化合物 (B) 的缩聚反应；以及 d) 乳化剂 (D)、所述工艺的特征在于，至少有一部分二胺化合物（A）和二羧酸化合物（B）在水介质中以分散相的形式存在，其平均液滴直径为 40 至 500 纳米。