2-Isopropenyl-2-oxazolin-5-on | 24214-12-8

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二氢呋喃
• 英文名称: 2-Isopropenyl-2-oxazolin-5-on
• 英文别名: 2-isopropenyl-4H-oxazol-5-one；2-isopropenyl-1,3-oxazolin-5-one；2-prop-1-en-2-yl-4H-1,3-oxazol-5-one
• CAS: 24214-12-8
• 化学式: C₆H₇NO₂
• 分子量: 125.127
• InChiKey: QKYWQDWJDQHBPI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.7
• 重原子数：
  9
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  38.7
• 氢给体数：
  0
• 氢受体数：
  3

文献信息

• FUNCTIONALIZED COPOLYMERS AND USE THEREOF
  申请人：3M INNOVATIVE PROPERTIES COMPANY

  公开号：US20210031152A1

  公开（公告）日：2021-02-04

  An article that includes a functionalized copolymer and the use thereof, particularly in a process for binding biomaterials, such as in a process for separating aggregated proteins from monomeric proteins in a biological solution; wherein the article includes: a) a porous substrate; and b) a copolymer covalently attached to the porous substrate, the copolymer comprising a hydrocarbon backbone and a plurality of pendant groups attached to the hydrocarbon backbone, wherein 1) each of a first plurality of pendant groups comprises: (a) at least one acidic group or salt thereof; and (b) a spacer group that directly links the at least one acidic group or salt thereof to the hydrocarbon backbone by a chain of at least 6 catenated atoms; and 2) each of a second plurality of pendant groups comprises: (a) at least one acidic group or salt thereof; and (b) a spacer group that directly links the at least one acidic group or salt thereof to the hydrocarbon backbone by a chain of at least 6 catenated atoms; and wherein the first plurality of pendant groups are different than the second plurality of pendant groups; and wherein a mole ratio of the first plurality of pendant groups to the second plurality of pendant groups is in a range of 95:5 to 5:95.

  一篇包括功能化共聚物及其用途的文章，特别是在结合生物材料的过程中使用，例如在从生物溶液中分离聚集蛋白质和单体蛋白质的过程中；其中该文章包括：a) 多孔基底；和 b) 共价连接到多孔基底上的共聚物，该共聚物包括一个碳氢骨架和多个连接到碳氢骨架上的挂链基团，其中1) 第一多数挂链基团中的每一个包括：(a) 至少一个酸性基团或其盐；和 (b) 一个通过至少6个串联原子链直接将至少一个酸性基团或其盐连接到碳氢骨架的空间基团；和 2) 第二多数挂链基团中的每一个包括：(a) 至少一个酸性基团或其盐；和 (b) 一个通过至少6个串联原子链直接将至少一个酸性基团或其盐连接到碳氢骨架的空间基团；其中第一多数挂链基团不同于第二多数挂链基团；并且第一多数挂链基团与第二多数挂链基团的摩尔比在95:5到5:95的范围内。
• [EN] PROCESSES FOR SEPARATING AGGREGATED PROTEINS FROM MONOMERIC PROTEINS IN A BIOLOGICAL SOLUTION<br/>[FR] PROCÉDÉS DE SÉPARATION DE PROTÉINES AGRÉGÉES À PARTIR DE PROTÉINES MONOMÈRES DANS UNE SOLUTION BIOLOGIQUE
  申请人：3M INNOVATIVE PROPERTIES CO

  公开号：WO2018048698A1

  公开（公告）日：2018-03-15

  A process for separating aggregated proteins from monomeric proteins in a biological solution, the process including: providing at least one filter element having a contacting surface, wherein the filter element comprises filter media comprising: a porous substrate; and disposed on the porous substrate, a polymer comprising a hydrocarbon backbone and a plurality of pendant groups attached to the hydrocarbon backbone, wherein each of a first plurality of pendant groups comprises: (1) at least one acidic group or salt thereof; and (2) a spacer group that directly links the at least one acidic group or salt thereof to the hydrocarbon backbone by a chain of at least 6 catenated atoms; and allowing an initial biological solution to contact the contacting surface of the filter element under conditions effective to separate the aggregated proteins from the monomeric proteins such that a final biological solution includes purified monomeric proteins.

  一种从生物溶液中分离聚集蛋白质和单体蛋白质的方法，该方法包括：提供至少一个具有接触表面的过滤元件，其中过滤元件包括包括过滤介质的多孔基质；并且在多孔基质上设置了一种聚合物，该聚合物包括一个烃骨架和附着在烃骨架上的多个偏基团，其中第一多个偏基团中的每一个包括：（1）至少一个酸性基团或其盐；和（2）一个间隔基团，通过至少6个串联原子的链将至少一个酸性基团或其盐直接连接到烃骨架；并且允许初始生物溶液在有效条件下接触过滤元件的接触表面，以使聚集蛋白质与单体蛋白质分离，从而得到含有纯化单体蛋白质的最终生物溶液。
• AZIRIDINE-FUNCTIONAL PHOTOACTIVE CROSSLINKING COMPOUNDS
  申请人：Zhu Peiwang

  公开号：US20100137469A1

  公开（公告）日：2010-06-03

  A photoactive compound that is the Michael addition reaction product of an aziridine compound and a photoinitiator-functional (meth)acrylate is described. The compound can be used to crosslink (meth)acrylic polymers via a hydrogen abstracting or an alpha-cleavage mechanism.

  描述了一种光活性化合物，它是氮杂环丙烷化合物和光引发剂官能基（甲基）丙烯酸酯的迈克尔加成反应产物。该化合物可通过氢抽取或α-裂解机制用于交联（甲基）丙烯酸聚合物。
• Reactive oligomers
  申请人：3M Innovative Properties Company

  公开号：US20030212210A1

  公开（公告）日：2003-11-13

  The present invention provides melt-processible adhesive compositions prepared from a first oligomer containing reactive functional groups capable of reaction at effective rates (at normal processing temperatures) with a co-reactive second component oligomer possessing functionality that is complementary to that of the first oligomer. The compositions may be used as coatings, including hard surface coatings, clear coatings, powder coatings and pattern coatings; as adhesives, including pressure sensitive adhesives and hot melt adhesives; as sealants; as optical coatings; as blown microfibers (BMF); as high refractive index optical materials; as barrier films; in microreplication; as low adhesion backsizes, (LABs) and as release coatings.

  本发明提供了可熔性粘合剂组合物，该组合物由第一低聚物制备而成，该低聚物含有反应性功能基团，能够在正常加工温度下与具有与第一低聚物相补充的功能性的共反应第二组分低聚物以有效速率发生反应。该组合物可用作涂层，包括硬表面涂层、透明涂层、粉末涂层和图案涂层；作为粘合剂，包括压敏粘合剂和热熔粘合剂；作为密封剂；作为光学涂层；作为吹塑微纤维（BMF）；作为高折射率光学材料；作为障碍膜；在微复制中使用；作为低粘附背面（LABs）和作为脱模涂层。
• Pressure sensitive adhesives possessing high load bearing capability
  申请人：3M Innovative Properties Company

  公开号：US20020132927A1

  公开（公告）日：2002-09-19

  Pressure sensitive adhesives are provided which possess high load bearing capabilities at elevated temperatures. The adhesives are prepared by polymerization of a syrup polymer composition having a first solute polymer having reactive, pendant functional groups, a second component having co-reactive functional groups, and a monomer mixture. The syrup polymer contains reactive electrophilic or nucleophilic functional groups that can subsequently crosslink by reaction with a second component having co-reactive functional groups.

  提供了具有高承载能力的压敏粘合剂，在高温下使用。该粘合剂是通过聚合糖浆聚合物组成物制备而成，其中第一溶质聚合物具有反应性的、悬挂的功能基团，第二组分具有共同反应的功能基团，以及单体混合物。糖浆聚合物含有反应性亲电性或亲核性功能基团，可以随后通过与具有共同反应功能基团的第二组分反应交联。