N-{4-[2-morpholin-4-yl-5-(4-oxo-3-o-tolyl-3,4-dihydro-quinazolin-2-yl)-thiophene-3-yl]-phenyl}-acetamide | 952614-02-7

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二氮杂萘
• 英文名称: N-{4-[2-morpholin-4-yl-5-(4-oxo-3-o-tolyl-3,4-dihydro-quinazolin-2-yl)-thiophene-3-yl]-phenyl}-acetamide
• 英文别名: N-[4-[5-[3-(2-methylphenyl)-4-oxoquinazolin-2-yl]-2-morpholin-4-ylthiophen-3-yl]phenyl]acetamide
• CAS: 952614-02-7
• 化学式: C₃₁H₂₈N₄O₃S
• 分子量: 536.654
• InChiKey: KLMNEZWENKWCQX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.4
• 重原子数：
  39
• 可旋转键数：
  5
• 环数：
  6.0
• sp3杂化的碳原子比例：
  0.19
• 拓扑面积：
  103
• 氢给体数：
  1
• 氢受体数：
  6

文献信息

• Thiazole and Thiophene Analogues, and Their Use in Treating Autoimmune Diseases and Cancers
  申请人：Giordano Anthony

  公开号：US20090306073A1

  公开（公告）日：2009-12-10

  Thiazole and thiophene compounds are disclosed having utility in treating inflammatory conditions, immunoinflammatory conditions, autoimmune diseases, and cancers. Methods for the synthesis of these compounds are also disclosed.
• US8217037B2
  申请人：——

  公开号：US8217037B2

  公开（公告）日：2012-07-10