[(dippe)Ni(η2-C,O-phthalimide)] | 1432726-49-2

• 英文名称: [(dippe)Ni(η2-C,O-phthalimide)]
• 英文别名: [(dippe)Ni(η²-C,O-phthalimide)]
• CAS: 1432726-49-2
• 化学式: C₂₂H₃₇NNiO₂P₂
• 分子量: 468.179
• InChiKey: QPMGQZGDAWQINW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
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• 重原子数：
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• 可旋转键数：
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• 环数：
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• sp3杂化的碳原子比例：
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• 拓扑面积：
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• 氢给体数：
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• 氢受体数：
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反应信息

• 作为产物：
  描述：

  邻苯二甲酸亚胺 、 ((1,2-bis(diisopropylphosphino)ethane)NiH)2 以 四氢呋喃 为溶剂， 生成 [(dippe)Ni(H)(phthalimide(-1H))] 、 [(dippe)Ni(η2-C,O-phthalimide)]
  参考文献：
  名称：

  Selective C═O Reduction in Phthalimide with Nickel(0) Compounds

  摘要：

  The catalytic reduction of phthalimide was achieved using nickel catalysts. The use of catalytic amounts (20% mol) of [Ni(COD)(2)] or [(dippe)Ni(mu-H)](2) (1) allowed the monoreduction of phthalimide to yield isoindolinone and benzamide, at 140-180 degrees C and 750 psi of H-2. When the N-H moiety of phthalimide was protected with a trimethylsilyl group, both C=O groups were reduced to yield (trimethylsilyl)isoindoline. However, when a methyl moiety was used as the protecting group, the C=O groups and the aromatic ring were reduced, using rather similar reaction conditions, due to the formation of 5 angstrom (average) nickel nanoparticles.

  DOI：

  10.1021/om400164g