2-[(3-hydroxy-6-chlorophenyl)amino]phenylacetic acid | 320777-35-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 酚类
• 英文名称: 2-[(3-hydroxy-6-chlorophenyl)amino]phenylacetic acid
• 英文别名: 2-[2-(2-Chloro-5-hydroxyanilino)phenyl]acetic acid
• CAS: 320777-35-3
• 化学式: C₁₄H₁₂ClNO₃
• 分子量: 277.707
• InChiKey: VYXXWOMFLWPYLX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4
• 重原子数：
  19
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.07
• 拓扑面积：
  69.6
• 氢给体数：
  3
• 氢受体数：
  4

文献信息

• Albumin-binding compounds that prevent nonenzymatic glycation and that may be used for treatment of glycation-related pathologies
  申请人：——

  公开号：US20010034359A1

  公开（公告）日：2001-10-25

  The present invention is directed to compositions that inhibit the nonenzymatic glycation of albumin, as well as methods of using compounds that inhibit albumin glycation for the treatment of glycation-related pathologies.

  本发明涉及抑制白蛋白非酶促糖基化的组合物，并使用抑制白蛋白糖基化的化合物治疗糖基化相关病理的方法。
• ALBUMIN-BINDING COMPOUNDS THAT PREVENT NONENZYMATIC GLYCATION AND THAT MAY BE USED FOR TREATMENT OF GLYCATION-RELATED PATHOLOGIES
  申请人：EXOCELL, INC.

  公开号：EP1242069A2

  公开（公告）日：2002-09-25
• TRAPPING COMPOUNDS AND METHOD FOR IDENTIFYING REACTIVE METABOLITES
  申请人：Shinkyo Raku

  公开号：US20120028284A1

  公开（公告）日：2012-02-02

  A compound of formula (I) is useful to identify reactive metabolites. [X is CH 2 , and p, q and r are each independently 0 or 1 with a proviso that the compound wherein p is 0, q is 0 and r is 1 is excluded]
• US6355680B1
  申请人：——

  公开号：US6355680B1

  公开（公告）日：2002-03-12
• US6552077B2
  申请人：——

  公开号：US6552077B2

  公开（公告）日：2003-04-22