| 1314296-98-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 酚类
• CAS: 1314296-98-4
• 化学式: C₁₄H₁₃N₃O₂S₂
• 分子量: 319.408
• InChiKey: RNFITCAMWJGMRF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.2
• 重原子数：
  21.0
• 可旋转键数：
  4.0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.07
• 拓扑面积：
  66.54
• 氢给体数：
  2.0
• 氢受体数：
  5.0

反应信息

• 作为反应物：
  描述：

  [RuHCl(CO)(PPh₃)₃] 、 以 乙醇 、 苯 为溶剂， 生成
  参考文献：
  名称：

  Microbial Assay of Ruthenium(II) Thiosemicarbazone Complexes: Synthesis, Spectral Characterization, and Electrochemistry

  摘要：

  Ruthenium complexes are synthesized with Schiff bases derived from salicylaldehyde/o-hydroxyacetophenone/o-vanillin/2-hydroxy-1-naphthaldehyde with thiosemicarbazide and thiophenecarboxaldehyde. Ruthenium coordinates in a tetradendate manner with these N2O2 donor ligands, which are characterized by elemental analysis, IR, electronic, and (HNMR)-H-1, C-13 NMR spectral studies. The elemental analysis suggests the stoichiometry to be 1:1 (metal: ligand). The redox behavior of the complexes has been investigated by cyclic voltammetric technique in the potential range -2.0 to +2.0 V. All the complexes were screened for their antimicrobial activity against two bacteria and two fungi. Further, two of these complexes were tested for its binding with CT-DNA using absorption studies.

  DOI：

  10.1080/15533174.2011.568809